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    49ers vs Seahawks NFL Week 1 – Match Preview & Live Updates Sunday, September 07, 2025

    National Football League
    Seahawks
    Home
    07/09/2025
    4:05pm
    49ers
    Away
    Where To Watch Injuries Recent Matches Predicted Winner Futures Statistics

    Seahawks vs. 49ers: Detailed Breakdown

    The slate moves into Sunday with Seahawks at 49ers. Current point spread: Seahawks ; O/U: 43.5 ML: 49ers +114, Seahawks -134. Books list full pricing ahead of kickoff at 4:05 pm ET.

    Money Line +114 DraftKings -125 BetMGM
    Spread 1.5 -102 FanDuel -2.5 -105 DraftKings
    Over/Under -104 FanDuel DraftKings

    Matchup Overview

    • Teams: Seahawks vs 49ers
    • Date: Sunday, September 07, 2025
    • Time: 04:05 pm ET
    • Venue: Lumen Field

    Where To Watch Seahawks vs 49ers on Sunday

    Watch the full match on FOX.

    Injuries

    Seahawks
    49ers
    DeMarcus Lawrence
    – Quadricep
    Marquez Valdes-Scantling
    – Gameday Inactive
    Drew Lock
    – Personal
    Nick Emmanwori
    – Ankle
    Jalen Milroe
    – Gameday Inactive
    Uchenna Nwosu
    – Knee
    Coby Bryant
    – Personal
    Kenneth Walker III
    – Glute
    Cooper Kupp
    – Hamstring/Wrist
    Jaxon Smith-Njigba
    – Illness
    Ernest Jones IV
    – Shoulder
    Sam Darnold
    – Chest
    Tory Horton
    – Ankle
    John Rhys Plumlee
    – Undisclosed
    Elijah Arroyo
    – Groin
    Jake Bobo
    – Concussion
    Julian Love
    – Groin
    Devon Witherspoon
    – Knee
    D'Anthony Bell
    – Gameday Inactive
    Shaquill Griffin
    – Gameday Inactive
    Kenny McIntosh
    – Knee
    Zach Charbonnet
    – Foot
    Riq Woolen
    – Illness
    Nehemiah Pritchett
    – Hamstring
    Josh Jobe
    – Head
    AJ Finley
    – Knee
    Jacardia Wright
    – Undisclosed
    Jerrick Reed II
    – Gameday Inactive
    George Holani
    – Hamstring
    Isas Waxter
    – Knee
    Brady Russell
    – Wrist
    Ty Okada
    – Oblique
    Robbie Ouzts
    – Ankle
    Drake Thomas
    – Shoulder
    Tyrice Knight
    – Knee
    Jared Ivey
    – Gameday Inactive
    Boye Mafe
    – Toe
    Connor O'Toole
    – Gameday Inactive
    Derick Hall
    – Hip
    Tyreke Smith
    – Gameday Inactive
    Jalen Sundell
    – Ankle/Elbow
    Christian Haynes
    – Pectoral
    Michael Jerrell
    – Gameday Inactive
    Charles Cross
    – Finger
    Abraham Lucas
    – Elbow
    Luke Felix-Fualalo
    – Undisclosed
    Josh Jones
    – Ankle
    Anthony Bradford
    – Back
    Grey Zabel
    – Heel
    Bryce Cabeldue
    – Gameday Inactive
    Mason Richman
    – Gameday Inactive
    Amari Kight
    – Knee
    Eric Saubert
    – Calf
    Cody White
    – Shoulder
    Dareke Young
    – Hamstring
    Tyrone Broden
    – Undisclosed
    AJ Barner
    – Calf
    Nick Kallerup
    – Gameday Inactive
    Jarran Reed
    – Back
    Quinton Bohanna
    – Gameday Inactive
    Mike Morris
    – Concussion
    Brandon Pili
    – Knee
    Johnathan Hankins
    – Back
    Rylie Mills
    – Gameday Inactive
    Leonard Williams
    – Elbow/Shoulder
    Ameer Abdullah
    – Ribs
    Isaiah Prince
    – Knee
    Tre Tomlinson
    – Undisclosed
    Carter Bradley
    – Undisclosed
    Renardo Green
    – Neck
    Ricky Pearsall
    – Knee
    Deommodore Lenoir
    – Hip
    Kurtis Rourke
    – Knee
    Demarcus Robinson
    – Suspended
    Malik Mustapha
    – Knee
    Thomas Morstead
    – Back
    Mac Jones
    – Knee
    Brandon Aiyuk
    – Knee
    Brock Purdy
    – Left Shoulder/Toe
    Tanner Mordecai
    – Undisclosed
    Jauan Jennings
    – Calf
    Jordan Watkins
    – Gameday Inactive
    Jacob Cowing
    – Hamstring
    Upton Stout
    – Calf
    Tre Brown
    – Heel
    Christian McCaffrey
    – Calf
    Richie Grant
    – Knee
    Jason Pinnock
    – Heel
    Chase Lucas
    – Gameday Inactive
    Ji'Ayir Brown
    – Hamstring
    Darrell Luter Jr.
    – Achilles
    Jordan James
    – Gameday Inactive
    Eli Apple
    – Gameday Inactive
    Isaac Guerendo
    – Gameday Inactive
    Patrick Taylor Jr.
    – Shoulder
    Siran Neal
    – Head
    Dallis Flowers
    – Gameday Inactive
    Marques Sigle
    – Gameday Inactive
    Kyle Juszczyk
    – Concussion
    Nick Martin
    – Gameday Inactive
    Chazz Surratt
    – Ankle
    B.Huff
    – Ankle
    Tatum Bethune
    – Thigh
    Corey Kiner
    – Undisclosed
    Jakob Robinson
    – Forearm
    Robert Beal Jr.
    – Gameday Inactive
    Dee Winters
    – Knee
    Fred Warner
    – Ankle
    Drew Moss
    – Gameday Inactive
    Sebastian Valdez
    – Gameday Inactive
    Tarron Jackson
    – Neck
    Luke Gifford
    – Knee
    Curtis Robinson
    – Knee
    Austen Pleasants
    – Gameday Inactive
    Jake Brendel
    – Hamstring
    A.Dillard
    – Undisclosed
    Isaac Alarcon
    – Suspension
    Colton McKivitz
    – Calf
    Trent Williams
    – Knee
    Spencer Burford
    – Knee
    Connor Colby
    – Gameday Inactive
    Dominick Puni
    – Knee
    Ben Bartch
    – Undisclosed
    Trent Taylor
    – Undisclosed
    George Kittle
    – Hamstring
    Mason Pline
    – Undisclosed
    Kevin Givens
    – Pectoral
    Sam Okuayinonu
    – Shoulder
    Jordan Elliott
    – Ankle
    Kalia Davis
    – Groin
    Yetur Gross-Matos
    – Undisclosed
    Alfred Collins
    – Knee
    Nick Bosa
    – Neck
    Mykel Williams
    – Knee
    CJ West
    – Knee

    Current Betting Odds

    • Spread: Seahawks favored at 2
    • Total (Over/Under): 43.5
    • Moneyline Odds: Seahawks +114 , 49ers -134

    Recent Matches

    Seahawks
    49ers
    Date Vs Result Score
    08/23/2025 Packers loss 20 : 7
    08/15/2025 Chiefs win 33 : 16
    08/07/2025 Raiders draw 23 : 23
    01/05/2025 Rams win 25 : 30
    12/26/2024 Bears win 3 : 6
    12/22/2024 Vikings loss 24 : 27
    12/15/2024 Packers loss 13 : 30
    12/08/2024 Cardinals win 18 : 30
    12/01/2024 Jets win 21 : 26
    11/24/2024 Cardinals win 16 : 6
    W - 6
    D - 1
    L - 3
    Date Vs Result Score
    08/23/2025 Chargers win 30 : 23
    08/16/2025 Raiders win 19 : 22
    08/09/2025 Broncos loss 9 : 30
    01/05/2025 Cardinals loss 47 : 24
    12/30/2024 Lions loss 34 : 40
    12/22/2024 Dolphins loss 29 : 17
    12/12/2024 Rams loss 6 : 12
    12/08/2024 Bears win 38 : 13
    12/01/2024 Bills loss 35 : 10
    11/24/2024 Packers loss 38 : 10
    W - 3
    L - 7

    Who Wins: our Prediction

    Based on statistical analysis, we see the Seahawks at a win probability of 55%, while the 49ers have a propability of 45% to win.

    Find the best Futures for Seahawks vs 49ers

    Statistics

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    All Betting Tips
    Money Line -116 FanDuel +100 BetMGM
    Spread -1.5 -105 DraftKings 1.0 -110 BetMGM
    Over/Under -102 FanDuel DraftKings
    Money Line +176 FanDuel -200 BetMGM
    Spread 3.5 -102 FanDuel -3.5 -105 BetMGM
    Over/Under -108 DraftKings DraftKings
    Money Line +130 DraftKings -152 FanDuel
    Spread 3.0 -115 BetMGM -3.0 -102 DraftKings
    Over/Under -108 DraftKings DraftKings
    Money Line +455 DraftKings -592 FanDuel
    Spread 10.0 -105 BetMGM -10.5 -104 FanDuel
    Over/Under -110 BetMGM DraftKings
    Money Line -120 BetMGM +106 FanDuel
    Spread -1.5 -105 BetMGM 1.5 -110 FanDuel
    Over/Under -108 FanDuel DraftKings
    Money Line -180 DraftKings +154 BetMGM
    Spread -3.5 +100 DraftKings 3.5 -115 BetMGM
    Over/Under -110 FanDuel DraftKings
    Money Line +135 BetMGM -150 Fanatics
    Spread 2.5 -102 FanDuel -3.0 -102 BetMGM
    Over/Under -108 FanDuel DraftKings
    Money Line -1299 Fanatics +950 DraftKings
    Spread -14.5 +100 FanDuel 14.0 -105 Fanatics
    Over/Under -105 Fanatics DraftKings
    Money Line -375 BetMGM +320 DraftKings
    Spread -7.5 -105 BetMGM 7.5 -105 BetMGM
    Over/Under -105 DraftKings DraftKings
    Money Line -190 BetMGM +164 DraftKings
    Spread -3.5 -105 DraftKings 3.5 -110 Fanatics
    Over/Under -105 FanDuel DraftKings
    Money Line +187.5 FanDuel -218 DraftKings
    Spread 4.5 -114 FanDuel -4.5 -105 DraftKings
    Over/Under -102 DraftKings DraftKings
    Money Line +370 DraftKings -450 Fanatics
    Spread 8.5 -105 FanDuel -8.5 -108 DraftKings
    Over/Under -108 FanDuel DraftKings
    Money Line +300 BetMGM -350 FanDuel
    Spread 7.0 -102 FanDuel -7.5 +100 DraftKings
    Over/Under -108 DraftKings DraftKings
    Money Line +810 FanDuel -1000 BetMGM
    Spread 13.5 -106 FanDuel -13.5 -105 DraftKings
    Over/Under -105 DraftKings DraftKings
    Money Line -115 Fanatics +102 FanDuel
    Spread -1.5 -105 DraftKings 1.5 -110 FanDuel
    Over/Under -110 FanDuel DraftKings
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