49ers host Giants on Sunday, November 02, 2025. Books show Point Spread Giants and O/U 48.5 ML: 49ers +122, Giants -143 is also posted. Numbers reflect current listings from sportsbooks.
Money Line+120-142
Spread
2.5
+100
-2.5
-110
Over/Under
+100
Matchup Overview
Teams: Giants vs 49ers
Date: Sunday, November 02, 2025
Time: 01:00 pm ET
Venue: MetLife Stadium
Where To Watch Giants vs 49ers on Sunday
The match will be broadcast by CBS.
Injuries
Giants
49ers
Brian Burns
– Foot
Gunner Olszewski
– Back
Malik Nabers
– Toe
Deonte Banks
– Personal
Russell Wilson
– Ankle
Kayvon Thibodeaux
– Shoulder
Jaxson Dart
– Hamstring
Jevón Holland
– Calf
Beaux Collins
– Hamstring
Graham Gano
– Groin
Da'Quan Felton
– Undisclosed
Jamie Gillan
– Left Knee
Jalin Hyatt
– Gameday Inactive
Tommy DeVito
– Gameday Inactive
Wan'Dale Robinson
– Ankle
Darius Slayton
– Groin
Jameis Winston
– Gameday Inactive
Eric Gray
– Knee
Paulson Adebo
– Shoulder
Dru Phillips
– Hip
Dane Belton
– Shoulder
Dante Miller
– Gameday Inactive
Korie Black
– Biceps
Tyler Nubin
– Non Injury Related (Personal)
Cor'Dale Flott
– Concussion
Tyrone Tracy Jr.
– Calf
TJ Moore
– Leg
Nic Jones
– Hamstring
Art Green
– Hip
Rushawn Baker
– Knee
Tre Hawkins III
– Undisclosed
Micah McFadden
– Lower Leg
Demetrius Flannigan-Fowles
– Calf
Cam Skattebo
– Knee
Ty Summers
– Undisclosed
Jermaine Terry II
– Undisclosed
Chris Board
– Chest
Abdul Carter
– Hamstring
Victor Dimukeje
– Pectoral
Darius Muasau
– Concussion
James Hudson
– Gameday Inactive
Chauncey Golston
– Neck
Bobby Okereke
– Shoulder
John Michael Schmitz Jr.
– Ankle
Jermaine Eluemunor
– Shoulder/Back
Evan Neal
– Gameday Inactive
Greg Van Roten
– Shoulder
Joshua Ezeudu
– Undisclosed
Jon Runyan
– Back
Andrew Thomas
– Foot
Daniel Bellinger
– Neck
Theo Johnson
– Toe
Chris Manhertz
– Illness
Thomas Fidone II
– Gameday Inactive
Bryce Ford-Wheaton
– Knee
Elijah Garcia
– Gameday Inactive
Darius Alexander
– Gameday Inactive
Rakeem Nuñez-Roches
– Foot
Roy Robertson-Harris
– Knee
Dexter Lawrence II
– Elbow
D.J. Davidson
– Foot
Jordon Riley
– Achilles
Ameer Abdullah
– Ribs
Isaiah Prince
– Knee
Tre Tomlinson
– Undisclosed
Carter Bradley
– Undisclosed
Renardo Green
– Neck
Ricky Pearsall
– Knee
Deommodore Lenoir
– Hip
Kurtis Rourke
– Knee
Demarcus Robinson
– Suspended
Malik Mustapha
– Knee
Thomas Morstead
– Back
Mac Jones
– Knee
Brandon Aiyuk
– Knee
Brock Purdy
– Left Shoulder/Toe
Tanner Mordecai
– Undisclosed
Jauan Jennings
– Calf
Jordan Watkins
– Gameday Inactive
Jacob Cowing
– Hamstring
Upton Stout
– Calf
Tre Brown
– Heel
Christian McCaffrey
– Calf
Richie Grant
– Knee
Jason Pinnock
– Heel
Chase Lucas
– Gameday Inactive
Ji'Ayir Brown
– Hamstring
Darrell Luter Jr.
– Achilles
Jordan James
– Gameday Inactive
Eli Apple
– Gameday Inactive
Isaac Guerendo
– Gameday Inactive
Patrick Taylor Jr.
– Shoulder
Siran Neal
– Head
Dallis Flowers
– Gameday Inactive
Marques Sigle
– Gameday Inactive
Kyle Juszczyk
– Concussion
Nick Martin
– Gameday Inactive
Chazz Surratt
– Ankle
B.Huff
– Ankle
Tatum Bethune
– Thigh
Corey Kiner
– Undisclosed
Jakob Robinson
– Forearm
Robert Beal Jr.
– Gameday Inactive
Dee Winters
– Knee
Fred Warner
– Ankle
Drew Moss
– Gameday Inactive
Sebastian Valdez
– Gameday Inactive
Tarron Jackson
– Neck
Luke Gifford
– Knee
Curtis Robinson
– Knee
Austen Pleasants
– Gameday Inactive
Jake Brendel
– Hamstring
A.Dillard
– Undisclosed
Isaac Alarcon
– Suspension
Colton McKivitz
– Calf
Trent Williams
– Knee
Spencer Burford
– Knee
Connor Colby
– Gameday Inactive
Dominick Puni
– Knee
Ben Bartch
– Undisclosed
Trent Taylor
– Undisclosed
George Kittle
– Hamstring
Mason Pline
– Undisclosed
Kevin Givens
– Pectoral
Sam Okuayinonu
– Shoulder
Jordan Elliott
– Ankle
Kalia Davis
– Groin
Yetur Gross-Matos
– Undisclosed
Alfred Collins
– Knee
Nick Bosa
– Neck
Mykel Williams
– Knee
CJ West
– Knee
Current Betting Odds
Spread: Giants favored at 2.5
Total (Over/Under): 48.5
Moneyline Odds: Giants +122 , 49ers -143
Recent Matches
Giants
49ers
Date
Vs
Result
Score
10/26/2025
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loss
38 :
20
10/19/2025
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loss
33 :
32
10/09/2025
Eagles
win
34
: 17
10/05/2025
Saints
loss
26 :
14
09/28/2025
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win
21
: 18
09/21/2025
Chiefs
loss
9
: 22
09/14/2025
Cowboys
loss
40 :
37
09/07/2025
Commanders
loss
21 :
6
08/21/2025
Patriots
win
42
: 10
08/16/2025
Jets
win
31
: 12
W - 4
L - 6
Date
Vs
Result
Score
10/26/2025
Texans
loss
26 :
15
10/19/2025
Falcons
win
20
: 10
10/12/2025
Buccaneers
loss
30 :
19
10/02/2025
Rams
win
23 :
26
09/28/2025
Jaguars
loss
21
: 26
09/21/2025
Cardinals
win
16
: 15
09/14/2025
Saints
win
21 :
26
09/07/2025
Seahawks
win
13 :
17
08/23/2025
Chargers
win
30
: 23
08/16/2025
Raiders
win
19 :
22
W - 7
L - 3
Who Wins: our Prediction
Based on statistical analysis, we see the Giants at a win probability of 57%, while the 49ers have a propability of 43% to win.
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