The 49ers host the Texans this Sunday at NRG Stadium. Books show the point spread (49ers ) and the total at 42. The 49ers host the Texans this Sunday at NRG Stadium. Books show the point spread (49ers ) and the total at 42. M/L: 49ers -153, Texans +130 Numbers reflect current sportsbook listings.
Money Line-148+130
Spread
-3.0
-105
2.5
+100
Over/Under
-110
Matchup Overview
Teams: Texans vs 49ers
Date: Sunday, October 26, 2025
Time: 01:00 pm ET
Venue: NRG Stadium
Where To Watch Texans vs 49ers on Sunday
The match will be broadcast by FOX.
Injuries
Texans
49ers
Azeez Al-Shaair
– Knee/Illness
Tank Dell
– Knee
Kamari Lassiter
– Knee
Jalen Pitre
– Rib
C.J. Stroud
– Concussion
Brevin Jordan
– Knee
Davis Mills
– Elbow
T.Smith
– Personal
Nico Collins
– Concussion
Christian Kirk
– Hamstring
Ka'imi Fairbairn
– Right Quad
Braxton Berrios
– Chest
Graham Mertz
– Gameday Inactive
Jimmie Ward
– Foot
Nick Chubb
– Foot
Jawhar Jordan
– Ankle
C.Gardner-Johnson
– Knee
Derek Stingley Jr.
– Abdomen
Myles Bryant
– Ankle
Woody Marks
– Calf
Joe Mixon
– Foot
M.J. Stewart
– Knee
Jaylin Smith
– Hamstring
Dameon Pierce
– Quad
Nick Niemann
– Pectoral
Jaylen Reed
– Undisclosed
Jake Hansen
– Elbow
Alijah Huzzie
– Knee
Austin Brinkman
– Knee
Damon Arnette
– Ankle
Luke Lachey
– Undisclosed
Jakob Johnson
– Hamstring
British Brooks
– Gameday Inactive
E.J. Speed
– Quadriceps
K.C. Ossai
– Undisclosed
Christian Harris
– Gameday Inactive
Solomon Byrd
– Gameday Inactive
Will Anderson Jr.
– Quad
Darrell Taylor
– Hip
Jamal Hill
– Hamstring
Blake Fisher
– Ankle
Kyonte Hamilton
– Ankle
Jake Andrews
– Foot
Haggai Ndubuisi
– Undisclosed
Marlon Davidson
– Undisclosed
Ed Ingram
– Abdomen
Tytus Howard
– Ankle/Knee
Tommy Togiai
– Gameday Inactive
Cam Robinson
– Illness
Laken Tomlinson
– Gameday Inactive
Austin Deculus
– Gameday Inactive
Trent Brown
– Knee
Aireontae Ersery
– Thumb
Jaylin Noel
– Undisclosed
Irv Smith Jr.
– Ankle
Justin Watson
– Undisclosed
Dalton Schultz
– Knee/Shoulder
Cade Stover
– Foot
Johnny Johnson III
– Undisclosed
Xavier Johnson
– Undisclosed
Sheldon Rankins
– Knee
Folorunso Fatukasi
– Undisclosed
Dylan Horton
– Knee
Kurt Hinish
– Shoulder
Derek Barnett
– Undisclosed
Denico Autry
– Knee
Mario Edwards Jr.
– Pectoral
Tim Settle Jr.
– Foot
Ameer Abdullah
– Ribs
Isaiah Prince
– Knee
Tre Tomlinson
– Undisclosed
Carter Bradley
– Undisclosed
Renardo Green
– Neck
Ricky Pearsall
– Knee
Deommodore Lenoir
– Hip
Kurtis Rourke
– Knee
Demarcus Robinson
– Suspended
Malik Mustapha
– Knee
Thomas Morstead
– Back
Mac Jones
– Knee
Brandon Aiyuk
– Personal
Brock Purdy
– Left Shoulder/Toe
Tanner Mordecai
– Undisclosed
Jauan Jennings
– Calf
Jordan Watkins
– Gameday Inactive
Jacob Cowing
– Hamstring
Upton Stout
– Calf
Tre Brown
– Heel
Christian McCaffrey
– Calf
Richie Grant
– Knee
Jason Pinnock
– Heel
Chase Lucas
– Undisclosed
Ji'Ayir Brown
– Hamstring
Darrell Luter Jr.
– Achilles
Jordan James
– Gameday Inactive
Eli Apple
– Gameday Inactive
Isaac Guerendo
– Gameday Inactive
Patrick Taylor Jr.
– Shoulder
Siran Neal
– Head
Dallis Flowers
– Undisclosed
Marques Sigle
– Gameday Inactive
Kyle Juszczyk
– Concussion
Nick Martin
– Gameday Inactive
Chazz Surratt
– Ankle
B.Huff
– Ankle
Tatum Bethune
– Thigh
Corey Kiner
– Undisclosed
Jakob Robinson
– Forearm
Robert Beal Jr.
– Gameday Inactive
Dee Winters
– Knee
Fred Warner
– Ankle
Drew Moss
– Gameday Inactive
Sebastian Valdez
– Gameday Inactive
Tarron Jackson
– Neck
Luke Gifford
– Knee
Curtis Robinson
– Knee
Matt Hennessy
– Neck
Austen Pleasants
– Gameday Inactive
Jake Brendel
– Hamstring
A.Dillard
– Undisclosed
Isaac Alarcon
– Suspension
Colton McKivitz
– Calf
Trent Williams
– Knee
Spencer Burford
– Knee
Connor Colby
– Gameday Inactive
Dominick Puni
– Knee
Ben Bartch
– Undisclosed
Trent Taylor
– Undisclosed
George Kittle
– Achilles
Mason Pline
– Undisclosed
Kevin Givens
– Pectoral
Sam Okuayinonu
– Shoulder
Jordan Elliott
– Ankle
Kalia Davis
– Groin
Yetur Gross-Matos
– Undisclosed
Alfred Collins
– Shoulder
Jonathan Garvin
– Undisclosed
Nick Bosa
– Neck
Mykel Williams
– Knee
CJ West
– Knee
Current Betting Odds
Spread: 49ers favored at 2.5
Total (Over/Under): 42
Moneyline Odds: Texans -153 , 49ers +130
Recent Matches
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49ers
Date
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win
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: 3
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loss
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loss
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W - 4
L - 6
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Vs
Result
Score
10/19/2025
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win
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: 10
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Buccaneers
loss
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19
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win
23 :
26
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loss
21
: 26
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win
16
: 15
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win
21 :
26
09/07/2025
Seahawks
win
13 :
17
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win
30
: 23
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win
19 :
22
08/09/2025
Broncos
loss
9
: 30
W - 7
L - 3
Who Wins: our Prediction
Based on statistical analysis, we see the Texans at a win probability of 42%, while the 49ers have a propability of 58% to win.
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