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    49ers vs Cardinals NFL Week 11 – Match Preview & Live Updates Sunday, November 16, 2025

    National Football League
    Cardinals
    Home
    16/11/2025
    4:05pm
    49ers
    Away
    Where To Watch Injuries Recent Matches Predicted Winner Futures Statistics

    Cardinals vs. 49ers: Detailed Breakdown

    The slate moves into Sunday with Cardinals at 49ers. Current point spread: Cardinals ; O/U: 48.5 ML: 49ers +158, Cardinals -187. Books list full pricing ahead of kickoff at 4:05 pm ET.

    Money Line +160 DraftKings -190 BetMGM
    Spread 3.5 -105 BetMGM -3.5 -105 DraftKings
    Over/Under -106 FanDuel DraftKings

    Matchup Overview

    • Teams: Cardinals vs 49ers
    • Date: Sunday, November 16, 2025
    • Time: 04:05 pm ET
    • Venue: State Farm Stadium

    Where To Watch Cardinals vs 49ers on Sunday

    Watch the full match on FOX.

    Injuries

    Cardinals
    49ers
    Will Johnson
    – Groin
    Kyler Murray
    – Illness
    Mack Wilson Sr.
    – Ankle
    Budda Baker
    – Hamstring
    Greg Dortch
    – Collarbone
    Baron Browning
    – Concussion
    James Conner
    – Ankle
    BJ Ojulari
    – Undisclosed
    J.Sweat
    – Ankle
    Blake Gillikin
    – Back
    Kei'Trel Clark
    – Gameday Inactive
    Michael Wilson
    – Foot
    Quez Watkins
    – Undisclosed
    Max Melton
    – Hamstring
    Zay Jones
    – Knee
    Marvin Harrison Jr.
    – Concussion
    DeeJay Dallas
    – Gameday Inactive
    Garrett Williams
    – Knee
    Sean Murphy-Bunting
    – Knee
    Starling Thomas V
    – Knee
    Zaven Collins
    – Hand
    Jammie Robinson
    – Gameday Inactive
    Akeem Davis-Gaither
    – Elbow
    Elijah Jones
    – Gameday Inactive
    Denzel Burke
    – Knee
    Darren Hall
    – Ankle
    Emari Demercado
    – Ankle
    Joey Blount
    – Neck
    Trey Benson
    – Knee
    Jalen Thompson
    – Hamstring
    Bam Knight
    – Gameday Inactive
    Kitan Crawford
    – Ankle
    Jaylon Jones
    – Hamstring
    Dadrion Taylor-Demerson
    – Ankle
    Owen Pappoe
    – Quadricep
    Cody Simon
    – Concussion
    J.J. Russell
    – Concussion
    Xavier Thomas
    – Gameday Inactive
    Dante Stills
    – Heel
    Darius Robinson
    – Chest
    Hayden Conner
    – Gameday Inactive
    Jon Gaines II
    – Thumb
    Evan Brown
    – Hamstring
    Jeremiah Byers
    – Gameday Inactive
    Kelvin Beachum
    – Knee
    Valentin Senn
    – Neck
    Paris Johnson Jr.
    – Knee
    Hjalte Froholdt
    – Elbow
    Jonah Williams
    – Foot
    Christian Jones
    – Knee
    Josh Fryar
    – Gameday Inactive
    PJ Mustipher
    – Gameday Inactive
    Simi Fehoko
    – Concussion
    Travis Vokolek
    – Gameday Inactive
    Andre Baccellia
    – Arm
    Elijah Higgins
    – Illness
    Trishton Jackson
    – Thumb
    Tip Reiman
    – Foot
    Xavier Weaver
    – Gameday Inactive
    L.J. Collier
    – Knee
    Bilal Nichols
    – Undisclosed
    Dalvin Tomlinson
    – Knee
    Elijah Simmons
    – Gameday Inactive
    Walter Nolen III
    – Calf
    Justin Jones
    – Knee
    Ameer Abdullah
    – Ribs
    Isaiah Prince
    – Knee
    Tre Tomlinson
    – Undisclosed
    Carter Bradley
    – Undisclosed
    Renardo Green
    – Neck
    Ricky Pearsall
    – Knee
    Deommodore Lenoir
    – Hip
    Kurtis Rourke
    – Knee
    Demarcus Robinson
    – Suspended
    Malik Mustapha
    – Knee
    Thomas Morstead
    – Back
    Mac Jones
    – Knee
    Brandon Aiyuk
    – Knee
    Brock Purdy
    – Left Shoulder/Toe
    Tanner Mordecai
    – Undisclosed
    Jauan Jennings
    – Calf
    Jordan Watkins
    – Gameday Inactive
    Jacob Cowing
    – Hamstring
    Upton Stout
    – Calf
    Tre Brown
    – Heel
    Christian McCaffrey
    – Calf
    Richie Grant
    – Knee
    Jason Pinnock
    – Heel
    Chase Lucas
    – Gameday Inactive
    Ji'Ayir Brown
    – Hamstring
    Darrell Luter Jr.
    – Achilles
    Jordan James
    – Gameday Inactive
    Eli Apple
    – Gameday Inactive
    Isaac Guerendo
    – Gameday Inactive
    Patrick Taylor Jr.
    – Shoulder
    Siran Neal
    – Head
    Dallis Flowers
    – Gameday Inactive
    Marques Sigle
    – Gameday Inactive
    Kyle Juszczyk
    – Concussion
    Nick Martin
    – Gameday Inactive
    Chazz Surratt
    – Ankle
    B.Huff
    – Ankle
    Tatum Bethune
    – Thigh
    Corey Kiner
    – Undisclosed
    Jakob Robinson
    – Forearm
    Robert Beal Jr.
    – Gameday Inactive
    Dee Winters
    – Knee
    Fred Warner
    – Ankle
    Drew Moss
    – Gameday Inactive
    Sebastian Valdez
    – Gameday Inactive
    Tarron Jackson
    – Neck
    Luke Gifford
    – Knee
    Curtis Robinson
    – Knee
    Austen Pleasants
    – Gameday Inactive
    Jake Brendel
    – Hamstring
    A.Dillard
    – Undisclosed
    Isaac Alarcon
    – Suspension
    Colton McKivitz
    – Calf
    Trent Williams
    – Knee
    Spencer Burford
    – Knee
    Connor Colby
    – Gameday Inactive
    Dominick Puni
    – Knee
    Ben Bartch
    – Undisclosed
    Trent Taylor
    – Undisclosed
    George Kittle
    – Hamstring
    Mason Pline
    – Undisclosed
    Kevin Givens
    – Pectoral
    Sam Okuayinonu
    – Shoulder
    Jordan Elliott
    – Ankle
    Kalia Davis
    – Groin
    Yetur Gross-Matos
    – Undisclosed
    Alfred Collins
    – Knee
    Nick Bosa
    – Neck
    Mykel Williams
    – Knee
    CJ West
    – Knee

    Current Betting Odds

    • Spread: Cardinals favored at 3.5
    • Total (Over/Under): 48.5
    • Moneyline Odds: Cardinals +158 , 49ers -187

    Recent Matches

    Cardinals
    49ers
    Date Vs Result Score
    11/09/2025 Seahawks loss 44 : 22
    11/03/2025 Cowboys win 17 : 27
    10/19/2025 Packers loss 23 : 27
    10/12/2025 Colts loss 31 : 27
    10/05/2025 Titans loss 21 : 22
    09/25/2025 Seahawks loss 20 : 23
    09/21/2025 49ers loss 16 : 15
    09/14/2025 Panthers win 27 : 22
    09/07/2025 Saints win 13 : 20
    08/23/2025 Raiders win 20 : 10
    W - 4
    L - 6
    Date Vs Result Score
    11/09/2025 Rams loss 26 : 42
    11/02/2025 Giants win 24 : 34
    10/26/2025 Texans loss 26 : 15
    10/19/2025 Falcons win 20 : 10
    10/12/2025 Buccaneers loss 30 : 19
    10/02/2025 Rams win 23 : 26
    09/28/2025 Jaguars loss 21 : 26
    09/21/2025 Cardinals win 16 : 15
    09/14/2025 Saints win 21 : 26
    09/07/2025 Seahawks win 13 : 17
    W - 6
    L - 4

    Who Wins: our Prediction

    Based on statistical analysis, we see the Cardinals at a win probability of 63%, while the 49ers have a propability of 37% to win.

    Find the best Futures for Cardinals vs 49ers

    Statistics

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    All Betting Tips
    Money Line -116 FanDuel +100 BetMGM
    Spread -1.5 -105 DraftKings 1.0 -110 BetMGM
    Over/Under -102 FanDuel DraftKings
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    Spread 3.5 -102 FanDuel -3.5 -105 BetMGM
    Over/Under -108 DraftKings DraftKings
    Money Line +130 DraftKings -152 FanDuel
    Spread 3.0 -115 BetMGM -3.0 -102 DraftKings
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    Spread 10.0 -105 BetMGM -10.5 -104 FanDuel
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    Money Line -180 DraftKings +154 BetMGM
    Spread -3.5 +100 DraftKings 3.5 -115 BetMGM
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    Money Line +135 BetMGM -150 Fanatics
    Spread 2.5 -102 FanDuel -3.0 -102 BetMGM
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    Money Line -1299 Fanatics +950 DraftKings
    Spread -14.5 +100 FanDuel 14.0 -105 Fanatics
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    Spread -7.5 -105 BetMGM 7.5 -105 BetMGM
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    Money Line -190 BetMGM +164 DraftKings
    Spread -3.5 -105 DraftKings 3.5 -110 Fanatics
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    Money Line +187.5 FanDuel -218 DraftKings
    Spread 4.5 -114 FanDuel -4.5 -105 DraftKings
    Over/Under -102 DraftKings DraftKings
    Money Line +370 DraftKings -450 Fanatics
    Spread 8.5 -105 FanDuel -8.5 -108 DraftKings
    Over/Under -108 FanDuel DraftKings
    Money Line +300 BetMGM -350 FanDuel
    Spread 7.0 -102 FanDuel -7.5 +100 DraftKings
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    Spread 13.5 -106 FanDuel -13.5 -105 DraftKings
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