For Saints at Patriots on Sunday, October 12, 2025, sportsbooks post Point Spread Saints with O/U 46 ML: Patriots +154, Saints -185 appears on boards. Kickoff is 1:00 pm ET. Lines are live at books.
Money Line+160-180
Spread
3.5
-115
-3.5
+100
Over/Under
-105
Matchup Overview
Teams: Saints vs Patriots
Date: Sunday, October 12, 2025
Time: 01:00 pm ET
Venue: Caesars Superdome
Where To Watch Saints vs Patriots on Sunday
The match will be broadcast by CBS.
Injuries
Saints
Patriots
Shane Lemieux
– Undisclosed
Ugo Amadi
– Gameday Inactive
Alontae Taylor
– Groin
Spencer Rattler
– Right Finger
Kendre Miller
– Knee
Tyler Shough
– Hip
Taysom Hill
– Knee (ACL)
Cedrick Wilson Jr.
– Knee
Chris Olave
– Hip
Velus Jones Jr.
– Knee
Mason Tipton
– Ilness
Bub Means
– Ankle
Justin Reid
– Knee
Rashid Shaheed
– Leg
Rejzohn Wright
– Gameday Inactive
Cam Akers
– Gameday Inactive
Isaac Yiadom
– Hamstring
Julian Blackmon
– Labrum Tear
Devin Neal
– Gameday Inactive
Jordan Howden
– Oblique
Jonas Sanker
– Head
Rico Payton
– Hamstring
Alvin Kamara
– Ankle
J.T. Gray
– Hamstring
Zach Wood
– Hamstring
Khalen Saunders
– Gameday Inactive
Cesar Ruiz
– Ankle
D'Marco Jackson
– Hamstring
Jonah Williams
– Gameday Inactive
Demario Davis
– Calf
Jonathan Bullard
– Gameday Inactive
Nick Saldiveri
– Knee
Landon Young
– Ankle
Torricelli Simpkins III
– Gameday Inactive
Barry Wesley
– Gameday Inactive
Trevor Penning
– Toe
Taliese Fuaga
– Knee
Will Clapp
– Foot
Dillon Radunz
– Toe
Erik McCoy
– Biceps
Juwan Johnson
– Ankle
Foster Moreau
– Knee
Jack Stoll
– Toe
Chris Tyree
– Lower Body
Bryan Bresee
– Back
Vernon Broughton
– Gameday Inactive
Nathan Shepherd
– Ankle/Knee
Cameron Jordan
– Groin
John Ridgeway III
– Gameday Inactive
Khristian Boyd
– Hand
Chris Rumph II
– Wrist
Chase Young
– Calf
Yasir Durant
– Undisclosed
Christian Gonzalez
– Concussion
Ja'Lynn Polk
– Shoulder
Harold Landry III
– Foot
DeMario Douglas
– Hamstring
Antonio Gibson
– Knee
Jabrill Peppers
– Quadricep
Carlton Davis III
– Achilles
Stefon Diggs
– Knee
Kayshon Boutte
– Shoulder
Drake Maye
– Right Shoulder
Mack Hollins
– Hand
Robert Spillane
– Hand
Marte Mapu
– Neck
Kobee Minor
– Gameday Inactive
Jaylinn Hawkins
– Hamstring
Marcus Epps
– Shoulder
Kyle Dugger
– Knee
Marcus Jones
– Elbow
Terrell Jennings
– Head
Marcellas Dial Jr.
– ACL
Alex Austin
– Undisclosed
Jeremiah Webb
– Undisclosed
Craig Woodson
– Ankle
TreVeyon Henderson
– Shoulder
Anfernee Jennings
– Knee
Lan Larison
– Undisclosed
Rhamondre Stevenson
– Toe
Brenden Schooler
– Ankle
Bradyn Swinson
– Gameday Inactive
K'Lavon Chaisson
– Knee
Brock Lampe
– Undisclosed
Jahlani Tavai
– Calf
Jack Gibbens
– Hamstring
Marcus Bryant
– Gameday Inactive
Christian Elliss
– Shoulder
Jared Wilson
– Thigh
Vederian Lowe
– Undisclosed
Layden Robinson
– Undisclosed
Garrett Bradbury
– Illness
Will Campbell
– Ankle
Isaiah Iton
– Hip
Caedan Wallace
– Gameday Inactive
Mike Onwenu
– Shoulder
Demontrey Jacobs
– Gameday Inactive
Morgan Moses
– Knee
Austin Hooper
– Undisclosed
CJ Dippre
– Illness
Kendrick Bourne
– Rib
Hunter Henry
– Knee
Efton Chism III
– Knee
Jack Westover
– Hamstring
Christian Barmore
– Personal
Elijah Ponder
– Gameday Inactive
Joshua Farmer
– Ankle
Jaquelin Roy
– Undisclosed
Khyiris Tonga
– Knee
M.Williams
– Ankle
Keion White
– Illness
Current Betting Odds
Spread: Saints favored at 3.5
Total (Over/Under): 46
Moneyline Odds: Saints +154 , Patriots -185
Recent Matches
Saints
Patriots
Date
Vs
Result
Score
10/05/2025
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win
26
: 14
09/28/2025
Bills
loss
31 :
19
09/21/2025
Seahawks
loss
44 :
13
09/14/2025
49ers
loss
21
: 26
09/07/2025
Cardinals
loss
13
: 20
08/23/2025
Broncos
loss
19
: 28
08/17/2025
Jaguars
draw
17
: 17
08/10/2025
Chargers
loss
27 :
13
01/05/2025
Buccaneers
loss
27 :
19
12/29/2024
Raiders
loss
10
: 25
W - 1
D - 1
L - 8
Date
Vs
Result
Score
10/05/2025
Bills
win
20 :
23
09/28/2025
Panthers
win
42
: 13
09/21/2025
Steelers
loss
14
: 21
09/14/2025
Dolphins
win
27 :
33
09/07/2025
Raiders
loss
13
: 20
08/21/2025
Giants
loss
42 :
10
08/16/2025
Vikings
win
12 :
20
08/08/2025
Commanders
win
48
: 18
01/05/2025
Bills
win
23
: 16
12/28/2024
Chargers
loss
7
: 40
W - 6
L - 4
Who Wins: our Prediction
Based on statistical analysis, we see the Saints at a win probability of 62%, while the Patriots have a propability of 38% to win.
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