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    Bills vs Patriots NFL Week 5 – Match Preview & Live Updates Sunday, October 05, 2025

    National Football League
    Bills
    05/10/2025
    8:20pm
    Patriots
    Where To Watch Injuries Recent Matches Predicted Winner Futures Statistics

    Bills vs. Patriots: Detailed Breakdown

    Bills vs Patriots is scheduled for Sunday, October 05, 2025 at 8:20 pm ET. Point Spread: Patriots ; O/U: 49.5 ML: Patriots -437, Bills +343. Lines are available across major sportsbetting sites.

    Money Line -395 DraftKings +350 BetMGM
    Spread -7.5 -105 FanDuel 7.5 -105 DraftKings
    Over/Under -110 BetMGM -108 DraftKings

    Matchup Overview

    • Teams: Bills vs Patriots
    • Date: Sunday, October 05, 2025
    • Time: 08:20 pm ET
    • Venue: Highmark Stadium

    Where To Watch Bills vs Patriots on Sunday

    Watch the full match on NBC.

    Injuries

    Bills
    Patriots
    Hayden Harris
    – Hamstring
    Keon Coleman
    – Groin
    Curtis Samuel
    – Gameday Inactive
    Tyler Bass
    – Left Hip/Groin
    Damar Hamlin
    – Pectoral
    James Cook
    – Hamstring
    Joshua Palmer
    – Ankle
    Taron Johnson
    – Groin
    Terrel Bernard
    – Hamstring
    Taylor Rapp
    – Nose
    Khalil Shakir
    – Ankle
    Jalen Virgil
    – Undisclosed
    Mike White
    – Gameday Inactive
    Elijah Moore
    – Personal
    Darrynton Evans
    – Undisclosed
    Ray Davis
    – Illness
    Tre'Davious White
    – Leg
    Brandon Codrington
    – Knee
    Wande Owens
    – Undisclosed
    Maxwell Hairston
    – Knee
    Te'Cory Couch
    – Hamstring
    Jordan Hancock
    – Shoulder
    Cam Lewis
    – Shoulder
    Dorian Williams
    – Knee
    Dorian Strong
    – Neck
    Shaq Thompson
    – Hamstring/Hand
    Ja'Marcus Ingram
    – Gameday Inactive
    Christian Benford
    – Groin
    Greg Rousseau
    – Knee
    Baylon Spector
    – Undisclosed
    Michael Hoecht
    – Suspension
    A.J. Epenesa
    – Pectoral
    Matt Milano
    – Pectoral
    Sedrick Van Pran-Granger
    – Undisclosed
    Connor McGovern
    – Hamstring
    Tylan Grable
    – Undisclosed
    Alec Anderson
    – Knee
    Dion Dawkins
    – Thumb
    Chase Lundt
    – Gameday Inactive
    Spencer Brown
    – Undisclosed
    Kaden Prather
    – Hamstring
    Jackson Hawes
    – Ankle
    Dalton Kincaid
    – Oblique
    Dawson Knox
    – Hip
    DeWayne Carter
    – Achilles
    Ed Oliver
    – Ankle
    DaQuan Jones
    – Calf
    Landon Jackson
    – Gameday Inactive
    Joey Bosa
    – Wrist
    T.J. Sanders
    – Knee
    Larry Ogunjobi
    – Suspension
    Yasir Durant
    – Undisclosed
    Christian Gonzalez
    – Hamstring
    Ja'Lynn Polk
    – Shoulder
    Harold Landry III
    – Foot
    Antonio Gibson
    – Knee
    Jabrill Peppers
    – Quadricep
    Carlton Davis III
    – Achilles
    Stefon Diggs
    – Knee
    Kayshon Boutte
    – Shoulder
    Mack Hollins
    – Hand
    Marte Mapu
    – Neck
    Jaylinn Hawkins
    – Hamstring
    Marcus Epps
    – Undisclosed
    Kyle Dugger
    – Knee
    Marcus Jones
    – Elbow
    Terrell Jennings
    – Knee
    Marcellas Dial Jr.
    – ACL
    Jeremiah Webb
    – Undisclosed
    Craig Woodson
    – Ankle
    TreVeyon Henderson
    – Knee
    Anfernee Jennings
    – Gameday Inactive
    Lan Larison
    – Undisclosed
    Rhamondre Stevenson
    – Toe
    K'Lavon Chaisson
    – Knee
    Brock Lampe
    – Undisclosed
    Jahlani Tavai
    – Calf
    Jack Gibbens
    – Hamstring
    Christian Elliss
    – Shoulder
    Jared Wilson
    – Thigh
    Vederian Lowe
    – Undisclosed
    Layden Robinson
    – Undisclosed
    Garrett Bradbury
    – Hip
    Will Campbell
    – Ankle
    Isaiah Iton
    – Hip
    Caedan Wallace
    – Gameday Inactive
    Mike Onwenu
    – Shoulder
    Demontrey Jacobs
    – Gameday Inactive
    Morgan Moses
    – Foot
    Austin Hooper
    – Undisclosed
    Kendrick Bourne
    – Rib
    Hunter Henry
    – Knee
    Efton Chism III
    – Knee
    Jack Westover
    – Hamstring
    Christian Barmore
    – Personal
    Elijah Ponder
    – Gameday Inactive
    Joshua Farmer
    – Ankle
    Jaquelin Roy
    – Undisclosed
    Khyiris Tonga
    – Knee
    M.Williams
    – Ankle
    Keion White
    – Illness

    Current Betting Odds

    • Spread: Patriots favored at 7.5
    • Total (Over/Under): 49.5
    • Moneyline Odds: Bills -437 , Patriots +343

    Recent Matches

    Bills
    Patriots
    Date Vs Result Score
    09/28/2025 Saints win 31 : 19
    09/18/2025 Dolphins win 31 : 21
    09/14/2025 Jets win 10 : 30
    09/07/2025 Ravens win 41 : 40
    08/23/2025 Buccaneers win 19 : 23
    08/17/2025 Bears loss 38 : 0
    08/09/2025 Giants loss 25 : 34
    01/26/2025 Chiefs loss 32 : 29
    01/19/2025 Ravens win 27 : 25
    01/12/2025 Broncos win 31 : 7
    W - 7
    L - 3
    Date Vs Result Score
    09/28/2025 Panthers win 42 : 13
    09/21/2025 Steelers loss 14 : 21
    09/14/2025 Dolphins win 27 : 33
    09/07/2025 Raiders loss 13 : 20
    08/21/2025 Giants loss 42 : 10
    08/16/2025 Vikings win 12 : 20
    08/08/2025 Commanders win 48 : 18
    01/05/2025 Bills win 23 : 16
    12/28/2024 Chargers loss 7 : 40
    12/22/2024 Bills loss 24 : 21
    W - 5
    L - 5

    Who Wins: our Prediction

    Based on statistical analysis, we see the Bills at a win probability of 22%, while the Patriots have a propability of 78% to win.

    Find the best Futures for Bills vs Patriots

    Statistics

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    All Betting Tips
    Money Line +145 Fanatics -164 FanDuel
    Spread 3.0 -105 DraftKings -3.5 -105 Fanatics
    Over/Under -110 BetMGM -105 DraftKings
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    Spread -4.5 -104 FanDuel 4.5 -112 DraftKings
    Over/Under -102 FanDuel -112 DraftKings
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    Spread -13.5 -105 DraftKings 13.0 -110 Fanatics
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    Spread 6.5 -105 DraftKings -6.5 -102 FanDuel
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    Spread -2.5 -115 FanDuel 2.5 -102 DraftKings
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    Spread 2.0 -110 BetMGM -2.5 -102 DraftKings
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    Over/Under -108 DraftKings -108 FanDuel
    Money Line -275 DraftKings +225 DraftKings
    Spread -6.5 -105 FanDuel 6.0 -110 DraftKings
    Over/Under -108 DraftKings -112 DraftKings
    Money Line -170 DraftKings +146 FanDuel
    Spread -3.0 -112 DraftKings 3.0 -104 FanDuel
    Over/Under -105 DraftKings -115 DraftKings
    Money Line -180 Fanatics +160 FanDuel
    Spread -3.5 -102 DraftKings 3.5 -114 FanDuel
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    Money Line -148 DraftKings +126 FanDuel
    Spread -3.0 -105 Fanatics 2.5 -102 DraftKings
    Over/Under -108 DraftKings -112 DraftKings
    Money Line -375 Fanatics +320 FanDuel
    Spread -7.5 +100 BetMGM 7.0 -102 DraftKings
    Over/Under -105 DraftKings -115 DraftKings
    Money Line -270 DraftKings +245 Fanatics
    Spread -5.5 -105 BetMGM 5.5 -102 FanDuel
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    Money Line -370 FanDuel +300 DraftKings
    Spread -7.0 -105 DraftKings 7.0 -110 Fanatics
    Over/Under -105 DraftKings -115 DraftKings
    Money Line -355 DraftKings +300 BetMGM
    Spread -7.0 -105 DraftKings 6.5 -102 FanDuel
    Over/Under -105 DraftKings -115 DraftKings
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