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    49ers vs Rams NFL Week 10 – Match Preview & Live Updates Sunday, November 09, 2025

    National Football League
    49ers
    09/11/2025
    4:25pm
    Rams
    Where To Watch Injuries Recent Matches Predicted Winner Futures Statistics

    49ers vs. Rams: Detailed Breakdown

    49ers travel to Rams for Sunday’s game. Books post Point Spread 49ers and Total 49.5 M/L: Rams +215, 49ers -263 is on offer. Kick time is 4:25 pm ET.

    Money Line +215 FanDuel -250 DraftKings
    Spread 5.5 -105 DraftKings -6.0 -105 BetMGM
    Over/Under -110 DraftKings -110 DraftKings

    Matchup Overview

    • Teams: 49ers vs Rams
    • Date: Sunday, November 09, 2025
    • Time: 04:25 pm ET
    • Venue: Levi's Stadium

    Where To Watch 49ers vs Rams on Sunday

    The match will be broadcast by FOX.

    Injuries

    49ers
    Rams
    Ameer Abdullah
    – Ribs
    Isaiah Prince
    – Knee
    Tre Tomlinson
    – Undisclosed
    Carter Bradley
    – Undisclosed
    Renardo Green
    – Neck
    Ricky Pearsall
    – Knee
    Deommodore Lenoir
    – Hip
    Kurtis Rourke
    – Knee
    Demarcus Robinson
    – Suspended
    Malik Mustapha
    – Knee
    Thomas Morstead
    – Back
    Mac Jones
    – Knee
    Brandon Aiyuk
    – Knee
    Brock Purdy
    – Left Shoulder/Toe
    Tanner Mordecai
    – Undisclosed
    Jauan Jennings
    – Calf
    Jordan Watkins
    – Gameday Inactive
    Jacob Cowing
    – Hamstring
    Upton Stout
    – Calf
    Tre Brown
    – Heel
    Christian McCaffrey
    – Calf
    Richie Grant
    – Knee
    Jason Pinnock
    – Heel
    Darrell Luter Jr.
    – Achilles
    Jordan James
    – Gameday Inactive
    Eli Apple
    – Gameday Inactive
    Isaac Guerendo
    – Back
    Patrick Taylor Jr.
    – Shoulder
    Siran Neal
    – Head
    Marques Sigle
    – Gameday Inactive
    Kyle Juszczyk
    – Concussion
    Nick Martin
    – Concussion
    Chazz Surratt
    – Ankle
    B.Huff
    – Ankle
    Tatum Bethune
    – Thigh
    Corey Kiner
    – Undisclosed
    Jakob Robinson
    – Forearm
    Robert Beal Jr.
    – Gameday Inactive
    Dee Winters
    – Knee
    Fred Warner
    – Ankle
    Drew Moss
    – Gameday Inactive
    Sebastian Valdez
    – Gameday Inactive
    Tarron Jackson
    – Neck
    Luke Gifford
    – Knee
    Curtis Robinson
    – Knee
    Austen Pleasants
    – Gameday Inactive
    Jake Brendel
    – Hamstring
    A.Dillard
    – Undisclosed
    Isaac Alarcon
    – Suspension
    Colton McKivitz
    – Calf
    Trent Williams
    – Knee
    Spencer Burford
    – Knee
    Connor Colby
    – Gameday Inactive
    Dominick Puni
    – Knee
    Ben Bartch
    – Undisclosed
    Trent Taylor
    – Undisclosed
    George Kittle
    – Hamstring
    Mason Pline
    – Undisclosed
    Kevin Givens
    – Pectoral
    Sam Okuayinonu
    – Shoulder
    Jordan Elliott
    – Ankle
    Kalia Davis
    – Groin
    Yetur Gross-Matos
    – Undisclosed
    Alfred Collins
    – Knee
    Nick Bosa
    – Neck
    Mykel Williams
    – Knee
    CJ West
    – Knee
    Byron Young
    – Knee
    Derion Kendrick
    – Gameday Inactive
    Ahkello Witherspoon
    – Knee
    Tutu Atwell
    – Hamstring
    Drake Stoops
    – Suspension
    Jared Verse
    – Knee
    Puka Nacua
    – Ankle
    Stetson Bennett
    – Gameday Inactive
    Konata Mumpfield
    – Calf
    Joshua Karty
    – Gameday Inactive
    Davante Adams
    – Hamstring
    Terrance Ferguson
    – Gameday Inactive
    Xavier Smith
    – Concussion
    Charles Woods
    – Concussion/Groin
    Blake Corum
    – Ankle
    Kyren Williams
    – Ankle
    Darious Williams
    – Shoulder
    Kamren Kinchens
    – Shoulder
    A.J. Green
    – Gameday Inactive
    Josh Wallace
    – Knee
    Nick Hampton
    – Illness
    Cody Schrader
    – Gameday Inactive
    Jarquez Hunter
    – Gameday Inactive
    Quentin Lake
    – Elbow
    Shaun Jolly
    – Undisclosed
    Josaiah Stewart
    – Concussion
    Brennan Jackson
    – Foot
    Alex Ward
    – Gameday Inactive
    Omar Speights
    – Ankle
    Beaux Limmer
    – Gameday Inactive
    Nate Landman
    – Calf
    Braden Fiske
    – Oblique
    Ty Hamilton
    – Gameday Inactive
    Willie Lampkin
    – Knee
    Justin Dedich
    – Gameday Inactive
    David Quessenberry
    – Gameday Inactive
    Kevin Dotson
    – Ankle
    KT Leveston
    – Gameday Inactive
    D.J. Humphries
    – Gameday Inactive
    Steve Avila
    – Ankle
    Alaric Jackson
    – Illness
    Rob Havenstein
    – Ankle
    Colby Parkinson
    – Shoulder
    Davis Allen
    – Knee
    Jordan Whittington
    – Back
    Tyler Higbee
    – Hip
    Kobie Turner
    – Back
    Desjuan Johnson
    – Gameday Inactive
    Poona Ford
    – Calf
    Keir Thomas
    – Undisclosed

    Current Betting Odds

    • Spread: 49ers favored at 6
    • Total (Over/Under): 49.5
    • Moneyline Odds: 49ers +215 , Rams -263

    Recent Matches

    49ers
    Rams
    Date Vs Result Score
    11/02/2025 Giants win 24 : 34
    10/26/2025 Texans loss 26 : 15
    10/19/2025 Falcons win 20 : 10
    10/12/2025 Buccaneers loss 30 : 19
    10/02/2025 Rams win 23 : 26
    09/28/2025 Jaguars loss 21 : 26
    09/21/2025 Cardinals win 16 : 15
    09/14/2025 Saints win 21 : 26
    09/07/2025 Seahawks win 13 : 17
    08/23/2025 Chargers win 30 : 23
    W - 7
    L - 3
    Date Vs Result Score
    11/02/2025 Saints win 34 : 10
    10/19/2025 Jaguars win 7 : 35
    10/12/2025 Ravens win 3 : 17
    10/02/2025 49ers loss 23 : 26
    09/28/2025 Colts win 27 : 20
    09/21/2025 Eagles loss 33 : 26
    09/14/2025 Titans win 19 : 33
    09/07/2025 Texans win 14 : 9
    08/23/2025 Browns loss 19 : 17
    08/16/2025 Chargers win 23 : 22
    W - 7
    L - 3

    Who Wins: our Prediction

    Based on statistical analysis, we see the 49ers at a win probability of 70%, while the Rams have a propability of 30% to win.

    Find the best Futures for 49ers vs Rams

    Statistics

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    All Betting Tips
    Money Line -135 BetMGM +124 DraftKings
    Spread -2.5 -114 FanDuel 2.5 -105 DraftKings
    Over/Under -105 FanDuel -110 DraftKings
    Money Line +132 FanDuel -148 DraftKings
    Spread 2.5 -102 FanDuel -3.0 -105 Fanatics
    Over/Under -105 FanDuel -105 DraftKings
    Money Line +100 DraftKings -116 FanDuel
    Spread 1.0 -110 Fanatics -1.5 -105 FanDuel
    Over/Under -110 DraftKings -110 DraftKings
    Money Line -250 BetMGM +220 FanDuel
    Spread -6.0 -108 DraftKings 5.5 -105 Fanatics
    Over/Under -105 DraftKings -115 DraftKings
    Money Line -800 BetMGM +660 FanDuel
    Spread -12.5 -108 DraftKings 11.5 -102 FanDuel
    Over/Under -105 DraftKings -115 DraftKings
    Money Line -500 Fanatics +430 FanDuel
    Spread -9.5 -115 DraftKings 9.5 -105 DraftKings
    Over/Under -105 DraftKings -115 DraftKings
    Money Line -952 DraftKings +660 FanDuel
    Spread -13.5 -105 Fanatics 13.5 -110 BetMGM
    Over/Under -108 FanDuel -110 DraftKings
    Money Line -375 Fanatics +320 FanDuel
    Spread -7.5 -110 DraftKings 7.5 -110 DraftKings
    Over/Under -110 FanDuel -105 DraftKings
    Money Line +132 FanDuel -150 BetMGM
    Spread 2.5 +100 DraftKings -3.0 -105 Fanatics
    Over/Under -110 DraftKings -110 DraftKings
    Money Line -901 BetMGM +750 DraftKings
    Spread -14.0 -110 BetMGM 13.5 +100 DraftKings
    Over/Under -108 DraftKings -112 DraftKings
    Money Line -250 DraftKings +215 FanDuel
    Spread -6.0 -110 DraftKings 5.5 -104 FanDuel
    Over/Under -110 BetMGM +100 DraftKings
    Money Line -901 DraftKings +650 BetMGM
    Spread -12.5 -108 DraftKings 12.5 -106 FanDuel
    Over/Under -110 DraftKings -110 DraftKings
    Money Line +116 FanDuel -130 DraftKings
    Spread 2.5 -110 FanDuel -2.5 -105 DraftKings
    Over/Under -110 DraftKings -110 DraftKings
    Money Line -270 DraftKings +240 FanDuel
    Spread -6.5 -105 FanDuel 5.5 -105 Fanatics
    Over/Under -105 BetMGM -110 DraftKings
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