Bills vs Chargers NFL Week 3 – Match Preview & Live Updates Sunday, September 27, 2026

National Football League
Bills
Home
27/09/2026
1:00pm
Chargers
Away

Bills vs. Chargers: Detailed Breakdown

Chargers host Bills this Sunday at Highmark Stadium. Books show point spread (Chargers ) and total sitting at 50. M/L: Chargers -350, Bills +279. Numbers reflect current sportsbook listings at the time of writing.

Money Line -350 BetMGM +295 FanDuel
Spread -7.5 -102 FanDuel 7.0 -105 BetMGM
Over/Under -105 FanDuel FanDuel

Matchup Overview

  • Teams: Bills vs Chargers
  • Date: Sunday, September 27, 2026
  • Time: 01:00 pm ET
  • Venue: Highmark Stadium

Where To Watch Bills vs Chargers on Sunday

Watch the full match on FOX.

Injuries

Bills
Chargers

Current Betting Odds

  • Spread: Chargers favored at 7
  • Total (Over/Under): 50
  • Moneyline Odds: Bills -350 , Chargers +279

Recent Matches

Bills
Chargers
Date Vs Result Score
09/17/2026 Lions win 41 : 31
09/13/2026 Texans win 31 : 36
08/27/2026 Steelers win 28 : 27
08/22/2026 Browns win 7 : 31
08/15/2026 Panthers win 29 : 14
01/17/2026 Broncos loss 33 : 30
01/11/2026 Jaguars win 24 : 27
01/04/2026 Jets win 35 : 8
12/28/2025 Eagles loss 12 : 13
12/21/2025 Browns win 20 : 23
W - 8
L - 2
Date Vs Result Score
09/20/2026 Raiders loss 14 : 26
09/13/2026 Cardinals loss 14 : 26
08/27/2026 Rams loss 18 : 20
08/20/2026 49ers loss 17 : 41
08/13/2026 Texans win 7 : 27
01/11/2026 Patriots loss 16 : 3
01/04/2026 Broncos loss 19 : 3
12/27/2025 Texans loss 16 : 20
12/21/2025 Cowboys win 17 : 34
12/14/2025 Chiefs win 13 : 16
W - 3
L - 7

Who Wins: our Prediction

Based on statistical analysis, we see the Bills at a win probability of 25%, while the Chargers have a propability of 75% to win.

Find the best Futures for Bills vs Chargers

Statistics

Want Even More Picks To Profit From?
Money Line +160 FanDuel -190 FanDuel
Spread 3.5 -110 BetMGM -3.5 -105 Fanatics
Over/Under -110 BetMGM FanDuel
Money Line +108 FanDuel -125 BetMGM
Spread 1.5 -105 FanDuel -1.5 -110 BetMGM
Over/Under -110 BetMGM FanDuel
Money Line +125 BetMGM -142 FanDuel
Spread 2.5 -105 FanDuel -2.5 -115 FanDuel
Over/Under -108 BetMGM FanDuel
Money Line -300 BetMGM +260 FanDuel
Spread -6.5 -112 BetMGM 6.5 -102 FanDuel
Over/Under -110 BetMGM FanDuel
Money Line -136 FanDuel +120 BetMGM
Spread -2.5 -110 FanDuel 2.5 -105 BetMGM
Over/Under -106 FanDuel FanDuel
Money Line +310 FanDuel -375 BetMGM
Spread 7.5 -110 BetMGM -7.5 -105 FanDuel
Over/Under -108 FanDuel FanDuel
Money Line +520 FanDuel -649 BetMGM
Spread 10.5 -105 FanDuel -10.5 -110 BetMGM
Over/Under -108 BetMGM FanDuel
Money Line -154 FanDuel +130 FanDuel
Spread -3.0 -102 BetMGM 2.5 -104 FanDuel
Over/Under -110 BetMGM FanDuel
Money Line -350 BetMGM +295 FanDuel
Spread -7.5 -102 FanDuel 7.0 -105 BetMGM
Over/Under -105 FanDuel FanDuel
Money Line -426 Fanatics +380 FanDuel
Spread -8.5 -108 BetMGM 8.5 -105 FanDuel
Over/Under -105 BetMGM FanDuel
Money Line +106 FanDuel -120 Fanatics
Spread 1.5 -110 FanDuel -1.5 -108 BetMGM
Over/Under -110 Fanatics FanDuel
Money Line +155 BetMGM -178 FanDuel
Spread 3.5 -112 BetMGM -3.5 -102 FanDuel
Over/Under -110 BetMGM BetMGM
Money Line -174 FanDuel +150 Fanatics
Spread -3.5 +100 Fanatics 3.0 -102 BetMGM
Over/Under -110 BetMGM FanDuel
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