Chiefs– is set for Sunday, December 21, 2025 at 1:00 pm ET. Sportsbooks list Point Spread Titans and Total 37.5 M/L: Chiefs +143, Titans -168 is available. Lines are posted across books.
Money Line+150-164
Spread
3.0
-102
-3.5
+102
Over/Under
-105
-110
Matchup Overview
Teams: Titans vs Chiefs
Date: Sunday, December 21, 2025
Time: 01:00 pm ET
Venue: Nissan Stadium
Where To Watch Titans vs Chiefs on Sunday
The match will be broadcast by CBS.
Injuries
Titans
Chiefs
Treylon Burks
– Collarbone
Calvin Ridley
– General Soreness
Cam Ward
– Ankle/Calf
Tyjae Spears
– Ankle
Johnny Hekker
– Illness
Tyler Lockett
– Knee
Elic Ayomanor
– Hamstring
Joey Slye
– Right Calf
Oluwafemi Oladejo
– Calf
Will Levis
– Shoulder
Van Jefferson
– Ankle
Mason Kinsey
– Gameday Inactive
James Proche II
– Gameday Inactive
Chimere Dike
– Chest
Tony Pollard
– Neck
Roger McCreary
– Hip
Kevin Winston Jr.
– Hamstring
Julius Wood
– Suspension
Xavier Woods
– Ankle
Marcus Harris
– Calf
Kalel Mullings
– Ankle
Jarvis Brownlee Jr.
– Ankle
Kendell Brooks
– Concussion
Julius Chestnut
– Back
Amani Hooker
– Ribs
L'Jarius Sneed
– Knee/Quad
Darrell Baker Jr.
– Head
Mike Brown
– Knee
Dre'Mont Jones
– Knee
Arden Key
– Pectoral
C.Barton
– Personal
Cedric Gray
– Concussion
James Williams
– Gameday Inactive
Jihad Ward
– Personal
JC Latham
– Hip
Anfernee Orji
– Knee
John Ojukwu
– Gameday Inactive
Corey Levin
– Neck
Jackson Slater
– Gameday Inactive
Chandler Brewer
– Undisclosed
Sebastian Joseph-Day
– Calf
Kevin Zeitler
– Hamstring
Cam Horsley
– Gameday Inactive
Blake Hance
– Shoulder
Dan Moore Jr.
– Ankle
Brandon Crenshaw-Dickson
– Gameday Inactive
Lloyd Cushenberry III
– Achilles
Bryce Oliver
– Knee
Josh Whyle
– Concussion
Matt Landers
– Undisclosed
Gunnar Helm
– Toe
Chig Okonkwo
– Foot
Xavier Restrepo
– Ankle
Thomas Odukoya
– Gameday Inactive
T'Vondre Sweat
– Mouth
James Lynch
– Shoulder
Jeffery Simmons
– Ankle
Ali Gaye
– Knee
Keaontay Ingram
– Undisclosed
Darius Rush
– Undisclosed
BJ Thompson
– Illness
Eric Scott Jr.
– Knee
Xavier Worthy
– Shoulder/Knee
Joshua Williams
– Gameday Inactive
Tyquan Thornton
– Head
Rashee Rice
– Suspended
Marquise Brown
– Ankle
Bryan Cook
– Ankle
Kristian Fulton
– Undisclosed
JuJu Smith-Schuster
– Knee
Isiah Pacheco
– Knee
Jalen Royals
– Knee
Jared Wiley
– Knee
Nazeeh Johnson
– Shoulder
Patrick Mahomes
– Right Wrist
Gardner Minshew
– Knee
Jaden Hicks
– Pectoral
Trent McDuffie
– Knee
Drue Tranquill
– Back
Skyy Moore
– Ankle
Elijah Mitchell
– Gameday Inactive
Deon Bush
– Achilles
Chamarri Conner
– Wrist
Kareem Hunt
– Calf
Chris Roland-Wallace
– Hand
Brashard Smith
– Illness
Jeffrey Bassa
– Knee
Nick Bolton
– Biceps
Mike Edwards
– Shoulder
Jaylen Watson
– Back
Melvin Smith Jr.
– Gameday Inactive
James Winchester
– Hamstring
Jack Cochrane
– Knee
Cam Jones
– Hip
Ajani Carter
– Hamstring
Brandon George
– Undisclosed
Mike Danna
– Quadriceps
Creed Humphrey
– Rib
Leo Chenal
– Shoulder
Omarr Norman-Lott
– Ankle
George Karlaftis
– Thumb
Hunter Nourzad
– Gameday Inactive
C.J. Hanson
– Gameday Inactive
Wanya Morris
– Gameday Inactive
Trey Smith
– Knee/Illness
Josh Simmons
– Illness
Jawaan Taylor
– Knee
Ethan Driskell
– Appendix
Kingsley Suamataia
– Concussion
Jaylon Moore
– Illness
Esa Pole
– Ankle
Nikko Remigio
– Thumb
Noah Gray
– Concussion/Shoulder
Jake Briningstool
– Hamstring
Jason Brownlee
– Gameday Inactive
Charles Omenihu
– Ankle
Felix Anudike-Uzomah
– Hamstring
Malik Herring
– Gameday Inactive
Chris Jones
– Personal
Ashton Gillotte
– Elbow
Janarius Robinson
– Foot
Jerry Tillery
– Elbow
Current Betting Odds
Spread: Titans favored at 3
Total (Over/Under): 37.5
Moneyline Odds: Titans +143 , Chiefs -168
Recent Matches
Titans
Chiefs
Date
Vs
Result
Score
12/14/2025
49ers
loss
37 :
24
12/07/2025
Browns
win
29 :
31
11/30/2025
Jaguars
loss
3
: 25
11/23/2025
Seahawks
loss
24
: 30
11/16/2025
Texans
loss
13
: 16
11/02/2025
Chargers
loss
20
: 27
10/26/2025
Colts
loss
38 :
14
10/19/2025
Patriots
loss
13
: 31
10/12/2025
Raiders
loss
20 :
10
10/05/2025
Cardinals
win
21 :
22
W - 2
L - 8
Date
Vs
Result
Score
12/14/2025
Chargers
loss
13
: 16
12/07/2025
Texans
loss
10
: 20
11/27/2025
Cowboys
loss
31 :
28
11/23/2025
Colts
win
23
: 20
11/16/2025
Broncos
loss
22 :
19
11/02/2025
Bills
loss
28 :
21
10/27/2025
Commanders
win
28
: 7
10/19/2025
Raiders
win
31
: 0
10/12/2025
Lions
win
30
: 17
10/06/2025
Jaguars
loss
31 :
28
W - 4
L - 6
Who Wins: our Prediction
Based on statistical analysis, we see the Titans at a win probability of 60%, while the Chiefs have a propability of 40% to win.
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