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    Chargers vs Chiefs NFL Week 1 – Match Preview & Live Updates Friday, September 05, 2025

    National Football League
    Chargers
    Home
    05/09/2025
    8:00pm
    Chiefs
    Away
    Where To Watch Injuries Recent Matches Predicted Winner Futures Statistics

    Chargers vs. Chiefs: Detailed Breakdown

    The slate moves into Friday with Chargers at Chiefs. Current point spread: Chargers ; O/U: 47.5 ML: Chiefs +149, Chargers -175. Books list full pricing ahead of kickoff at 8:00 pm ET.

    Money Line +145 DraftKings -165 BetMGM
    Spread 3.0 +100 DraftKings -3.0 -105 BetMGM
    Over/Under -105 FanDuel DraftKings

    Matchup Overview

    • Teams: Chargers vs Chiefs
    • Date: Friday, September 05, 2025
    • Time: 08:00 pm ET
    • Venue: Arena Corinthians

    Where To Watch Chargers vs Chiefs on Friday

    Watch the full match on YT.

    Injuries

    Chargers
    Chiefs
    Daiyan Henley
    – Groin
    Quentin Johnston
    – Concussion
    Elijah Molden
    – Knee
    Derwin James Jr.
    – Glute
    Denzel Perryman
    – Ankle
    Omarion Hampton
    – Ankle
    Tre Harris
    – Jaw
    Justin Herbert
    – Hand
    Derius Davis
    – Knee
    Ladd McConkey
    – Biceps
    Cam Hart
    – Hip
    Najee Harris
    – Eye
    Tony Jefferson
    – Hamstring
    Benjamin St-Juste
    – Groin
    Junior Colson
    – Shoulder
    Donte Jackson
    – Ankle
    RJ Mickens
    – Gameday Inactive
    Hassan Haskins
    – Chest
    Tarheeb Still
    – Ankle
    Kimani Vidal
    – Neck
    Trikweze Bridges
    – Knee
    Deane Leonard
    – Undisclosed
    Raheim Sanders
    – Gameday Inactive
    Jaylen Jones
    – Undisclosed
    Ja'Sir Taylor
    – Illness
    Jordan Oladokun
    – Undisclosed
    Emany Johnson
    – Gameday Inactive
    Dalevon Campbell
    – Gameday Inactive
    Eric Rogers
    – Undisclosed
    Kendall Williamson
    – Achilles
    Tucker Fisk
    – Gameday Inactive
    Troy Dye
    – Thumb
    Scott Matlock
    – Ankle
    McCallan Castles
    – Undisclosed
    Nikko Reed
    – Gameday Inactive
    Josh Harris
    – Undisclosed
    Bud Dupree
    – Hamstring
    Jordan Petaia
    – Undisclosed
    Caleb Murphy
    – Gameday Inactive
    Khalil Mack
    – Elbow
    Del'Shawn Phillips
    – Undisclosed
    Kyle Kennard
    – Gameday Inactive
    Kana'i Mauga
    – Gameday Inactive
    Jamaree Salyer
    – Knee
    Josh Fuga
    – Undisclosed
    Rashawn Slater
    – Knee
    Branson Taylor
    – Gameday Inactive
    M.Becton
    – Illness
    Bradley Bozeman
    – Back
    Joe Alt
    – Ankle
    Andre James
    – Neck
    Trey Pipkins III
    – Knee
    Brenden Rice
    – Undisclosed
    Tyler Conklin
    – Calf
    Keandre Lambert-Smith
    – Gameday Inactive
    Oronde Gadsden
    – Gameday Inactive
    Dez Fitzpatrick
    – Undisclosed
    Jalen Reagor
    – Undisclosed
    Will Dissly
    – Knee
    Teair Tart
    – Groin
    Da'Shawn Hand
    – Back
    Justin Eboigbe
    – Foot
    Otito Ogbonnia
    – Gameday Inactive
    Naquan Jones
    – Gameday Inactive
    Jamaree Caldwell
    – Illness
    Keaontay Ingram
    – Undisclosed
    Darius Rush
    – Undisclosed
    BJ Thompson
    – Illness
    Eric Scott Jr.
    – Knee
    Xavier Worthy
    – Shoulder/Knee
    Joshua Williams
    – Gameday Inactive
    Tyquan Thornton
    – Head
    Rashee Rice
    – Suspended
    Marquise Brown
    – Ankle
    Bryan Cook
    – Ankle
    Kristian Fulton
    – Undisclosed
    JuJu Smith-Schuster
    – Knee
    Isiah Pacheco
    – Knee
    Jalen Royals
    – Knee
    Jared Wiley
    – Knee
    Nazeeh Johnson
    – Suspension
    Patrick Mahomes
    – Right Wrist
    Gardner Minshew
    – Knee
    Jaden Hicks
    – Pectoral
    Trent McDuffie
    – Knee
    Drue Tranquill
    – Back
    Skyy Moore
    – Ankle
    Elijah Mitchell
    – Gameday Inactive
    Deon Bush
    – Achilles
    Chamarri Conner
    – Wrist
    Kareem Hunt
    – Calf
    Chris Roland-Wallace
    – Hand
    Brashard Smith
    – Illness
    Jeffrey Bassa
    – Knee
    Nick Bolton
    – Biceps
    Mike Edwards
    – Shoulder
    Jaylen Watson
    – Back
    Melvin Smith Jr.
    – Gameday Inactive
    James Winchester
    – Hamstring
    Jack Cochrane
    – Knee
    Cam Jones
    – Hip
    Ajani Carter
    – Hamstring
    Brandon George
    – Undisclosed
    Mike Danna
    – Quadriceps
    Creed Humphrey
    – Rib
    Leo Chenal
    – Knee
    Omarr Norman-Lott
    – Ankle
    George Karlaftis
    – Thumb
    Hunter Nourzad
    – Gameday Inactive
    C.J. Hanson
    – Gameday Inactive
    Wanya Morris
    – Gameday Inactive
    Trey Smith
    – Knee/Illness
    Josh Simmons
    – Illness
    Jawaan Taylor
    – Knee
    Ethan Driskell
    – Appendix
    Kingsley Suamataia
    – Concussion
    Jaylon Moore
    – Illness
    Esa Pole
    – Ankle
    Nikko Remigio
    – Thumb
    Noah Gray
    – Concussion/Shoulder
    Jake Briningstool
    – Hamstring
    Jason Brownlee
    – Gameday Inactive
    Charles Omenihu
    – Ankle
    Felix Anudike-Uzomah
    – Hamstring
    Malik Herring
    – Gameday Inactive
    Chris Jones
    – Personal
    Ashton Gillotte
    – Elbow
    Janarius Robinson
    – Foot
    Jerry Tillery
    – Elbow

    Current Betting Odds

    • Spread: Chargers favored at 3
    • Total (Over/Under): 47.5
    • Moneyline Odds: Chargers +149 , Chiefs -175

    Recent Matches

    Chargers
    Chiefs
    Date Vs Result Score
    08/23/2025 49ers loss 30 : 23
    08/16/2025 Rams loss 23 : 22
    08/10/2025 Saints win 27 : 13
    07/31/2025 Lions win 7 : 34
    01/11/2025 Texans loss 32 : 12
    01/05/2025 Raiders win 20 : 34
    12/28/2024 Patriots win 7 : 40
    12/19/2024 Broncos win 34 : 27
    12/15/2024 Buccaneers loss 17 : 40
    12/08/2024 Chiefs loss 19 : 17
    W - 5
    L - 5
    Date Vs Result Score
    08/22/2025 Bears loss 27 : 29
    08/15/2025 Seahawks loss 33 : 16
    08/09/2025 Cardinals loss 20 : 17
    02/09/2025 Eagles loss 40 : 22
    01/26/2025 Bills win 32 : 29
    01/18/2025 Texans win 23 : 14
    01/05/2025 Broncos loss 38 : 0
    12/25/2024 Steelers win 10 : 29
    12/21/2024 Texans win 27 : 19
    12/15/2024 Browns win 7 : 21
    W - 5
    L - 5

    Who Wins: our Prediction

    Based on statistical analysis, we see the Chargers at a win probability of 61%, while the Chiefs have a propability of 39% to win.

    Find the best Futures for Chargers vs Chiefs

    Statistics

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