Colts host Chiefs this Sunday at Arrowhead Stadium. Books show point spread (Colts ) and total sitting at 49.5. M/L: Colts -190, Chiefs +161. Numbers reflect current sportsbook listings at the time of writing.
Money Line-180+160
Spread
-3.5
-105
3.5
-105
Over/Under
-108
Matchup Overview
Teams: Chiefs vs Colts
Date: Sunday, November 23, 2025
Time: 01:00 pm ET
Venue: Arrowhead Stadium
Where To Watch Chiefs vs Colts on Sunday
The match will be broadcast by CBS.
Injuries
Chiefs
Colts
Keaontay Ingram
– Undisclosed
Darius Rush
– Undisclosed
BJ Thompson
– Illness
Eric Scott Jr.
– Knee
Xavier Worthy
– Shoulder/Knee
Joshua Williams
– Gameday Inactive
Tyquan Thornton
– Head
Rashee Rice
– Suspended
Marquise Brown
– Ankle
Bryan Cook
– Ankle
Kristian Fulton
– Undisclosed
JuJu Smith-Schuster
– Knee
Isiah Pacheco
– Knee
Jalen Royals
– Knee
Jared Wiley
– Knee
Nazeeh Johnson
– Suspension
Patrick Mahomes
– Right Wrist
Gardner Minshew
– Knee
Jaden Hicks
– Pectoral
Trent McDuffie
– Knee
Drue Tranquill
– Back
Skyy Moore
– Ankle
Elijah Mitchell
– Gameday Inactive
Deon Bush
– Achilles
Chamarri Conner
– Wrist
Kareem Hunt
– Calf
Chris Roland-Wallace
– Hand
Brashard Smith
– Illness
Jeffrey Bassa
– Knee
Nick Bolton
– Biceps
Mike Edwards
– Shoulder
Jaylen Watson
– Back
Melvin Smith Jr.
– Gameday Inactive
James Winchester
– Hamstring
Jack Cochrane
– Knee
Cam Jones
– Hip
Ajani Carter
– Hamstring
Brandon George
– Undisclosed
Mike Danna
– Quadriceps
Creed Humphrey
– Rib
Leo Chenal
– Knee
Omarr Norman-Lott
– Ankle
George Karlaftis
– Thumb
Hunter Nourzad
– Gameday Inactive
C.J. Hanson
– Gameday Inactive
Wanya Morris
– Gameday Inactive
Trey Smith
– Knee/Illness
Josh Simmons
– Illness
Jawaan Taylor
– Knee
Ethan Driskell
– Appendix
Kingsley Suamataia
– Concussion
Jaylon Moore
– Illness
Esa Pole
– Ankle
Nikko Remigio
– Thumb
Noah Gray
– Concussion/Shoulder
Jake Briningstool
– Hamstring
Jason Brownlee
– Gameday Inactive
Charles Omenihu
– Ankle
Felix Anudike-Uzomah
– Hamstring
Malik Herring
– Gameday Inactive
Chris Jones
– Personal
Ashton Gillotte
– Elbow
Janarius Robinson
– Foot
Jerry Tillery
– Elbow
Josh Downs
– Hamstring
D.J. Montgomery
– Undisclosed
Spencer Shrader
– Knee
Anthony Richardson Sr.
– Eye
Anthony Gould
– Illness
Charvarius Ward
– Concussion
Rigoberto Sanchez
– Personal
Adonai Mitchell
– Gameday Inactive
Michael Pittman Jr.
– Glute
Alec Pierce
– Knee
Riley Leonard
– Gameday Inactive
Ashton Dulin
– Concussion
Daniel Jones
– Fibula
Nick Cross
– Hip
DJ Giddens
– Gameday Inactive
Kenny Moore II
– Calf
Khalil Herbert
– Gameday Inactive
Justin Walley
– Knee
JuJu Brents
– Gameday Inactive
Hunter Wohler
– Foot
Tyler Goodson
– Elbow
Samuel Womack III
– Gameday Inactive
Johnathan Edwards
– Gameday Inactive
Salvon Ahmed
– Ankle
Daniel Scott
– Knee
Chris Lammons
– Foot
Jaylon Jones
– Hamstring
Zaire Franklin
– Ankle
Liam Anderson
– Undisclosed
Joe Bachie
– Quadricep
Maddux Trujillo
– Undisclosed
Sean McKeon
– Shoulder
Kwity Paye
– Groin
Samson Ebukam
– Back
Jacob Phillips
– Bicep
Quenton Nelson
– Wrist
Jaylon Carlies
– Ankle
Austin Ajiake
– Throat
Cameron McGrone
– Achilles
Tanor Bortolini
– Concussion
Danny Pinter
– Rib
Luke Tenuta
– Gameday Inactive
Dalton Tucker
– Shoulder
Matt Goncalves
– Personal
Braden Smith
– Groin
Blake Freeland
– Leg
Jack Wilson
– Undisclosed
Bernhard Raimann
– Illness
Jelani Woods
– Gameday Inactive
Tyler Warren
– Toe
Drew Ogletree
– Neck
Will Mallory
– Gameday Inactive
Grover Stewart
– Biceps
JT Tuimoloau
– Gameday Inactive
Neville Gallimore
– Knee
Tyquan Lewis
– Oblique
Laiatu Latu
– Hamstring
Eric Johnson II
– Gameday Inactive
DeForest Buckner
– Back
Current Betting Odds
Spread: Colts favored at 3.5
Total (Over/Under): 49.5
Moneyline Odds: Chiefs -190 , Colts +161
Recent Matches
Chiefs
Colts
Date
Vs
Result
Score
11/16/2025
Broncos
loss
22 :
19
11/02/2025
Bills
loss
28 :
21
10/27/2025
Commanders
win
28
: 7
10/19/2025
Raiders
win
31
: 0
10/12/2025
Lions
win
30
: 17
10/06/2025
Jaguars
loss
31 :
28
09/28/2025
Ravens
win
37
: 20
09/21/2025
Giants
win
9 :
22
09/14/2025
Eagles
loss
17
: 20
09/05/2025
Chargers
loss
27 :
21
W - 5
L - 5
Date
Vs
Result
Score
11/09/2025
Falcons
win
31
: 25
11/02/2025
Steelers
loss
27 :
20
10/26/2025
Titans
win
38
: 14
10/19/2025
Chargers
win
24 :
38
10/12/2025
Cardinals
win
31
: 27
10/05/2025
Raiders
win
40
: 6
09/28/2025
Rams
loss
27 :
20
09/21/2025
Titans
win
20 :
41
09/14/2025
Broncos
win
29
: 28
09/07/2025
Dolphins
win
33
: 8
W - 8
L - 2
Who Wins: our Prediction
Based on statistical analysis, we see the Chiefs at a win probability of 37%, while the Colts have a propability of 63% to win.
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