On Sunday, October 12, 2025, Chiefs face Lions. The Point Spread is Lions , while the Total is 51.5 M/L: Lions -148, Chiefs +125 is available. Sportsbetting sites have full lines listed.
Money Line-142+130
Spread
-2.5
-115
2.5
+100
Over/Under
-105
Matchup Overview
Teams: Chiefs vs Lions
Date: Sunday, October 12, 2025
Time: 08:20 pm ET
Venue: Arrowhead Stadium
Where To Watch Chiefs vs Lions on Sunday
Watch the full match on NBC.
Injuries
Chiefs
Lions
Keaontay Ingram
– Undisclosed
Darius Rush
– Undisclosed
BJ Thompson
– Illness
Eric Scott Jr.
– Knee
Xavier Worthy
– Shoulder/Knee
Joshua Williams
– Gameday Inactive
Tyquan Thornton
– Head
Rashee Rice
– Suspended
Marquise Brown
– Ankle
Bryan Cook
– Ankle
Kristian Fulton
– Undisclosed
JuJu Smith-Schuster
– Knee
Isiah Pacheco
– Knee
Jalen Royals
– Knee
Jared Wiley
– Knee
Nazeeh Johnson
– Shoulder
Patrick Mahomes
– Right Wrist
Gardner Minshew
– Knee
Jaden Hicks
– Pectoral
Trent McDuffie
– Knee
Drue Tranquill
– Back
Skyy Moore
– Ankle
Elijah Mitchell
– Gameday Inactive
Deon Bush
– Achilles
Chamarri Conner
– Wrist
Kareem Hunt
– Calf
Chris Roland-Wallace
– Hand
Brashard Smith
– Illness
Jeffrey Bassa
– Knee
Nick Bolton
– Biceps
Mike Edwards
– Shoulder
Jaylen Watson
– Back
Melvin Smith Jr.
– Gameday Inactive
James Winchester
– Hamstring
Jack Cochrane
– Knee
Cam Jones
– Hip
Ajani Carter
– Hamstring
Brandon George
– Undisclosed
Mike Danna
– Quadriceps
Creed Humphrey
– Rib
Leo Chenal
– Knee
Omarr Norman-Lott
– Ankle
George Karlaftis
– Thumb
Hunter Nourzad
– Gameday Inactive
C.J. Hanson
– Gameday Inactive
Wanya Morris
– Gameday Inactive
Trey Smith
– Knee/Illness
Josh Simmons
– Illness
Jawaan Taylor
– Knee
Ethan Driskell
– Appendix
Kingsley Suamataia
– Concussion
Jaylon Moore
– Illness
Esa Pole
– Ankle
Nikko Remigio
– Thumb
Noah Gray
– Concussion/Shoulder
Jake Briningstool
– Hamstring
Jason Brownlee
– Gameday Inactive
Charles Omenihu
– Ankle
Felix Anudike-Uzomah
– Hamstring
Malik Herring
– Gameday Inactive
Chris Jones
– Personal
Ashton Gillotte
– Elbow
Janarius Robinson
– Foot
Jerry Tillery
– Elbow
Justin Herron
– Undisclosed
D.J. Reed
– Cramps
David Montgomery
– Illness
Terrion Arnold
– Hamstring
Ennis Rakestraw Jr.
– Shoulder
Kalif Raymond
– Neck
Tim Patrick
– Groin
Craig Reynolds
– Gameday Inactive
Amon-Ra St. Brown
– Wrist
Grant Stuard
– Foot
Dicaprio Bootle
– Undisclosed
Isaac TeSlaa
– Illness
Dominic Lovett
– Gameday Inactive
Amik Robertson
– Hamstring
Rock Ya-Sin
– Lower Body
Loren Strickland
– Gameday Inactive
Kye Robichaux
– Undisclosed
Dan Jackson
– Leg
A.Maddox
– Hamstring
Khalil Dorsey
– Ankle
Kerby Joseph
– Knee
Brian Branch
– Toe/Ankle
Sione Vaki
– Hamstring
Alex Anzalone
– Illness
Erick Hallett
– Gameday Inactive
Nick Whiteside
– Gameday Inactive
Malcolm Rodriguez
– Knee
Jack Campbell
– Ankle
Ezekiel Turner
– Achilles
Jacob Saylors
– Back
Z.Cunningham
– Hamstring
Trevor Nowaske
– Elbow
Alim McNeill
– Knee
Derrick Barnes
– Knee
Penei Sewell
– Shoulder
Giovanni Manu
– Knee
Graham Glasgow
– Lower Leg
Michael Niese
– Gameday Inactive
Kingsley Eguakun
– Gameday Inactive
Trystan Colon
– Wrist
Taylor Decker
– Undisclosed
Tate Ratledge
– Knee
Dan Skipper
– Back
Miles Frazier
– Knee
Jamarco Jones
– Ankle
Christian Mahogany
– Knee
Kayode Awosika
– Shoulder
Colby Sorsdal
– Leg
Levi Onwuzurike
– Knee (ACL)
Shane Zylstra
– Ankle
Tom Kennedy
– Gameday Inactive
Sam LaPorta
– Back
Kenny Yeboah
– Undisclosed
Brock Wright
– Ankle
Chris Smith
– Gameday Inactive
Marcus Davenport
– Shoulder
Josh Paschal
– Undisclosed
Mekhi Wingo
– Undisclosed
Pat O'Connor
– Knee
Al-Quadin Muhammad
– Knee
Aidan Hutchinson
– Elbow
DJ Reader
– Back
Brodric Martin
– Gameday Inactive
Current Betting Odds
Spread: Lions favored at 2.5
Total (Over/Under): 51.5
Moneyline Odds: Chiefs -148 , Lions +125
Recent Matches
Chiefs
Lions
Date
Vs
Result
Score
10/06/2025
Jaguars
loss
31 :
28
09/28/2025
Ravens
win
37
: 20
09/21/2025
Giants
win
9 :
22
09/14/2025
Eagles
loss
17
: 20
09/05/2025
Chargers
loss
27 :
21
08/22/2025
Bears
loss
27
: 29
08/15/2025
Seahawks
loss
33 :
16
08/09/2025
Cardinals
loss
20 :
17
02/09/2025
Eagles
loss
40 :
22
01/26/2025
Bills
win
32
: 29
W - 3
L - 7
Date
Vs
Result
Score
10/05/2025
Bengals
win
24 :
37
09/28/2025
Browns
win
34
: 10
09/22/2025
Ravens
win
30 :
38
09/14/2025
Bears
win
52
: 21
09/07/2025
Packers
loss
27 :
13
08/23/2025
Texans
loss
7
: 26
08/16/2025
Dolphins
loss
17
: 24
08/08/2025
Falcons
win
10 :
17
07/31/2025
Chargers
loss
7
: 34
01/18/2025
Commanders
loss
31
: 45
W - 5
L - 5
Who Wins: our Prediction
Based on statistical analysis, we see the Chiefs at a win probability of 43%, while the Lions have a propability of 57% to win.
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