Chiefs vs Lions NFL Week 6 – Match Preview & Live Updates Sunday, October 12, 2025

National Football League
Chiefs
Home
12/10/2025
8:20pm
Lions
Away

Chiefs vs. Lions: Detailed Breakdown

On Sunday, October 12, 2025, Chiefs face Lions. The Point Spread is Lions , while the Total is 51.5 M/L: Lions -148, Chiefs +125 is available. Sportsbetting sites have full lines listed.

Money Line -142 DraftKings +130 FanDuel
Spread -2.5 -115 BetMGM 2.5 +100 Fanatics
Over/Under -105 FanDuel BetMGM

Matchup Overview

  • Teams: Chiefs vs Lions
  • Date: Sunday, October 12, 2025
  • Time: 08:20 pm ET
  • Venue: Arrowhead Stadium

Where To Watch Chiefs vs Lions on Sunday

Watch the full match on NBC.

Injuries

Chiefs
Lions
Keaontay Ingram
– Undisclosed
Darius Rush
– Undisclosed
BJ Thompson
– Illness
Eric Scott Jr.
– Knee
Xavier Worthy
– Shoulder/Knee
Joshua Williams
– Gameday Inactive
Tyquan Thornton
– Head
Rashee Rice
– Suspended
Marquise Brown
– Ankle
Bryan Cook
– Ankle
Kristian Fulton
– Undisclosed
JuJu Smith-Schuster
– Knee
Isiah Pacheco
– Knee
Jalen Royals
– Knee
Jared Wiley
– Knee
Nazeeh Johnson
– Shoulder
Patrick Mahomes
– Right Wrist
Gardner Minshew
– Knee
Jaden Hicks
– Pectoral
Trent McDuffie
– Knee
Drue Tranquill
– Back
Skyy Moore
– Ankle
Elijah Mitchell
– Gameday Inactive
Deon Bush
– Achilles
Chamarri Conner
– Wrist
Kareem Hunt
– Calf
Chris Roland-Wallace
– Hand
Brashard Smith
– Illness
Jeffrey Bassa
– Knee
Nick Bolton
– Biceps
Mike Edwards
– Shoulder
Jaylen Watson
– Back
Melvin Smith Jr.
– Gameday Inactive
James Winchester
– Hamstring
Jack Cochrane
– Knee
Cam Jones
– Hip
Ajani Carter
– Hamstring
Brandon George
– Undisclosed
Mike Danna
– Quadriceps
Creed Humphrey
– Rib
Leo Chenal
– Knee
Omarr Norman-Lott
– Ankle
George Karlaftis
– Thumb
Hunter Nourzad
– Gameday Inactive
C.J. Hanson
– Gameday Inactive
Wanya Morris
– Gameday Inactive
Trey Smith
– Knee/Illness
Josh Simmons
– Illness
Jawaan Taylor
– Knee
Ethan Driskell
– Appendix
Kingsley Suamataia
– Concussion
Jaylon Moore
– Illness
Esa Pole
– Ankle
Nikko Remigio
– Thumb
Noah Gray
– Concussion/Shoulder
Jake Briningstool
– Hamstring
Jason Brownlee
– Gameday Inactive
Charles Omenihu
– Ankle
Felix Anudike-Uzomah
– Hamstring
Malik Herring
– Gameday Inactive
Chris Jones
– Personal
Ashton Gillotte
– Elbow
Janarius Robinson
– Foot
Jerry Tillery
– Elbow
Justin Herron
– Undisclosed
D.J. Reed
– Cramps
David Montgomery
– Illness
Terrion Arnold
– Hamstring
Ennis Rakestraw Jr.
– Shoulder
Kalif Raymond
– Neck
Tim Patrick
– Groin
Craig Reynolds
– Gameday Inactive
Amon-Ra St. Brown
– Wrist
Grant Stuard
– Foot
Dicaprio Bootle
– Undisclosed
Isaac TeSlaa
– Illness
Dominic Lovett
– Gameday Inactive
Amik Robertson
– Hamstring
Rock Ya-Sin
– Lower Body
Loren Strickland
– Gameday Inactive
Kye Robichaux
– Undisclosed
Dan Jackson
– Leg
A.Maddox
– Hamstring
Khalil Dorsey
– Ankle
Kerby Joseph
– Knee
Brian Branch
– Toe/Ankle
Sione Vaki
– Hamstring
Alex Anzalone
– Illness
Erick Hallett
– Gameday Inactive
Nick Whiteside
– Gameday Inactive
Malcolm Rodriguez
– Knee
Jack Campbell
– Ankle
Ezekiel Turner
– Achilles
Jacob Saylors
– Back
Z.Cunningham
– Hamstring
Trevor Nowaske
– Elbow
Alim McNeill
– Knee
Derrick Barnes
– Knee
Penei Sewell
– Shoulder
Giovanni Manu
– Knee
Graham Glasgow
– Lower Leg
Michael Niese
– Gameday Inactive
Kingsley Eguakun
– Gameday Inactive
Trystan Colon
– Wrist
Taylor Decker
– Undisclosed
Tate Ratledge
– Knee
Dan Skipper
– Back
Miles Frazier
– Knee
Jamarco Jones
– Ankle
Christian Mahogany
– Knee
Kayode Awosika
– Shoulder
Colby Sorsdal
– Leg
Levi Onwuzurike
– Knee (ACL)
Shane Zylstra
– Ankle
Tom Kennedy
– Gameday Inactive
Sam LaPorta
– Back
Kenny Yeboah
– Undisclosed
Brock Wright
– Ankle
Chris Smith
– Gameday Inactive
Marcus Davenport
– Shoulder
Josh Paschal
– Undisclosed
Mekhi Wingo
– Undisclosed
Pat O'Connor
– Knee
Al-Quadin Muhammad
– Knee
Aidan Hutchinson
– Elbow
DJ Reader
– Back
Brodric Martin
– Gameday Inactive

Current Betting Odds

  • Spread: Lions favored at 2.5
  • Total (Over/Under): 51.5
  • Moneyline Odds: Chiefs -148 , Lions +125

Recent Matches

Chiefs
Lions
Date Vs Result Score
10/06/2025 Jaguars loss 31 : 28
09/28/2025 Ravens win 37 : 20
09/21/2025 Giants win 9 : 22
09/14/2025 Eagles loss 17 : 20
09/05/2025 Chargers loss 27 : 21
08/22/2025 Bears loss 27 : 29
08/15/2025 Seahawks loss 33 : 16
08/09/2025 Cardinals loss 20 : 17
02/09/2025 Eagles loss 40 : 22
01/26/2025 Bills win 32 : 29
W - 3
L - 7
Date Vs Result Score
10/05/2025 Bengals win 24 : 37
09/28/2025 Browns win 34 : 10
09/22/2025 Ravens win 30 : 38
09/14/2025 Bears win 52 : 21
09/07/2025 Packers loss 27 : 13
08/23/2025 Texans loss 7 : 26
08/16/2025 Dolphins loss 17 : 24
08/08/2025 Falcons win 10 : 17
07/31/2025 Chargers loss 7 : 34
01/18/2025 Commanders loss 31 : 45
W - 5
L - 5

Who Wins: our Prediction

Based on statistical analysis, we see the Chiefs at a win probability of 43%, while the Lions have a propability of 57% to win.

Find the best Futures for Chiefs vs Lions

Statistics

Want Even More Picks To Profit From?
Money Line -116 FanDuel +100 BetMGM
Spread -1.5 -105 DraftKings 1.0 -110 BetMGM
Over/Under -102 FanDuel DraftKings
Money Line +176 FanDuel -200 BetMGM
Spread 3.5 -102 FanDuel -3.5 -105 BetMGM
Over/Under -108 DraftKings DraftKings
Money Line +130 DraftKings -152 FanDuel
Spread 3.0 -115 BetMGM -3.0 -102 DraftKings
Over/Under -108 DraftKings DraftKings
Money Line +455 DraftKings -592 FanDuel
Spread 10.0 -105 BetMGM -10.5 -104 FanDuel
Over/Under -110 BetMGM DraftKings
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Spread -1.5 -105 BetMGM 1.5 -110 FanDuel
Over/Under -108 FanDuel DraftKings
Money Line -180 DraftKings +154 BetMGM
Spread -3.5 +100 DraftKings 3.5 -115 BetMGM
Over/Under -110 FanDuel DraftKings
Money Line +135 BetMGM -150 Fanatics
Spread 2.5 -102 FanDuel -3.0 -102 BetMGM
Over/Under -108 FanDuel DraftKings
Money Line -1299 Fanatics +950 DraftKings
Spread -14.5 +100 FanDuel 14.0 -105 Fanatics
Over/Under -105 Fanatics DraftKings
Money Line -375 BetMGM +320 DraftKings
Spread -7.5 -105 BetMGM 7.5 -105 BetMGM
Over/Under -105 DraftKings DraftKings
Money Line -190 BetMGM +164 DraftKings
Spread -3.5 -105 DraftKings 3.5 -110 Fanatics
Over/Under -105 FanDuel DraftKings
Money Line +187.5 FanDuel -218 DraftKings
Spread 4.5 -114 FanDuel -4.5 -105 DraftKings
Over/Under -102 DraftKings DraftKings
Money Line +370 DraftKings -450 Fanatics
Spread 8.5 -105 FanDuel -8.5 -108 DraftKings
Over/Under -108 FanDuel DraftKings
Money Line +300 BetMGM -350 FanDuel
Spread 7.0 -102 FanDuel -7.5 +100 DraftKings
Over/Under -108 DraftKings DraftKings
Money Line +810 FanDuel -1000 BetMGM
Spread 13.5 -106 FanDuel -13.5 -105 DraftKings
Over/Under -105 DraftKings DraftKings
Money Line -115 Fanatics +102 FanDuel
Spread -1.5 -105 DraftKings 1.5 -110 FanDuel
Over/Under -110 FanDuel DraftKings
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