Bills vs Lions NFL Week 2 – Match Preview & Live Updates Thursday, September 17, 2026

National Football League

Bills

Home

17/09/2026
8:15pm

Lions

Away

Bills vs. Lions: Detailed Breakdown

Lions host Bills this Thursday at Highmark Stadium. Books show point spread (Lions ) and total sitting at 54.5. M/L: Lions -231, Bills +190. Numbers reflect current sportsbook listings at the time of writing.

Thursday, September 17, 2026 • 8:15 PM ET • AMZN

Money Line -225 +194

Spread -4.5 -110 4.5 -105

Over/Under -112

Matchup Overview

• Teams: Bills vs Lions
• Date: Thursday, September 17, 2026
• Time: 08:15 pm ET
• Venue: Highmark Stadium

Where To Watch Bills vs Lions on Thursday

Watch the full match on AMZN.

Injuries

Bills

Lions

Current Betting Odds

• Spread: Lions favored at 5
• Total (Over/Under): 54.5
• Moneyline Odds: Bills -231 , Lions +190

Recent Matches

Bills

Lions

Date	Vs	Result	Score
09/13/2026	Texans	win	31 : 36
08/27/2026	Steelers	win	28 : 27
08/22/2026	Browns	win	7 : 31
08/15/2026	Panthers	win	29 : 14
01/17/2026	Broncos	loss	33 : 30
01/11/2026	Jaguars	win	24 : 27
01/04/2026	Jets	win	35 : 8
12/28/2025	Eagles	loss	12 : 13
12/21/2025	Browns	win	20 : 23
12/14/2025	Patriots	win	31 : 35

W - 8

L - 2

Date	Vs	Result	Score
09/13/2026	Saints	win	31 : 30
08/29/2026	Colts	win	16 : 25
08/22/2026	Commanders	win	17 : 13
08/13/2026	Bengals	loss	16 : 14
01/04/2026	Bears	win	16 : 19
12/25/2025	Vikings	loss	23 : 10
12/21/2025	Steelers	loss	24 : 29
12/14/2025	Rams	loss	41 : 34
12/04/2025	Cowboys	win	44 : 30
11/27/2025	Packers	loss	24 : 31

W - 5

L - 5

Who Wins: our Prediction

Based on statistical analysis, we see the Bills at a win probability of 33%, while the Lions have a propability of 67% to win.

Find the best Futures for Bills vs Lions

Statistics