Chargers travel to Broncos for Sunday’s game. Books post Point Spread Broncos and Total 45.5 M/L: Broncos -149, Chargers +126 is on offer. Kick time is 4:05 pm ET.
Money Line-150+132
Spread
-2.5
-120
2.5
+100
Over/Under
-110
Matchup Overview
Teams: Chargers vs Broncos
Date: Sunday, September 21, 2025
Time: 04:05 pm ET
Venue: SoFi Stadium
Where To Watch Chargers vs Broncos on Sunday
Watch the full match on CBS.
Injuries
Chargers
Broncos
Daiyan Henley
– Groin
Quentin Johnston
– Concussion
Elijah Molden
– Knee
Derwin James Jr.
– Glute
Denzel Perryman
– Ankle
Omarion Hampton
– Ankle
Tre Harris
– Jaw
Justin Herbert
– Hand
Derius Davis
– Knee
Ladd McConkey
– Biceps
Cam Hart
– Hip
Najee Harris
– Eye
Tony Jefferson
– Hamstring
Benjamin St-Juste
– Groin
Junior Colson
– Shoulder
Donte Jackson
– Ankle
RJ Mickens
– Gameday Inactive
Hassan Haskins
– Chest
Tarheeb Still
– Ankle
Kimani Vidal
– Neck
Trikweze Bridges
– Knee
Deane Leonard
– Undisclosed
Raheim Sanders
– Gameday Inactive
Jaylen Jones
– Undisclosed
Ja'Sir Taylor
– Illness
Jordan Oladokun
– Undisclosed
Emany Johnson
– Gameday Inactive
Dalevon Campbell
– Gameday Inactive
Eric Rogers
– Undisclosed
Kendall Williamson
– Achilles
Tucker Fisk
– Gameday Inactive
Troy Dye
– Thumb
Scott Matlock
– Ankle
McCallan Castles
– Undisclosed
Nikko Reed
– Gameday Inactive
Josh Harris
– Undisclosed
Bud Dupree
– Hamstring
Jordan Petaia
– Undisclosed
Caleb Murphy
– Gameday Inactive
Khalil Mack
– Elbow
Del'Shawn Phillips
– Undisclosed
Kyle Kennard
– Gameday Inactive
Kana'i Mauga
– Gameday Inactive
Jamaree Salyer
– Knee
Josh Fuga
– Undisclosed
Rashawn Slater
– Knee
Branson Taylor
– Gameday Inactive
M.Becton
– Illness
Bradley Bozeman
– Back
Joe Alt
– Ankle
Andre James
– Neck
Trey Pipkins III
– Knee
Brenden Rice
– Undisclosed
Tyler Conklin
– Calf
Keandre Lambert-Smith
– Gameday Inactive
Oronde Gadsden
– Gameday Inactive
Dez Fitzpatrick
– Undisclosed
Jalen Reagor
– Undisclosed
Will Dissly
– Knee
Teair Tart
– Groin
Da'Shawn Hand
– Back
Justin Eboigbe
– Foot
Otito Ogbonnia
– Gameday Inactive
Naquan Jones
– Gameday Inactive
Jamaree Caldwell
– Illness
Johnny Walker Jr.
– Lower Body
Jonathon Cooper
– Quad
Evan Engram
– Calf
Pat Surtain II
– Leg
Wil Lutz
– Illness
Sam Ehlinger
– Gameday Inactive
Trent Sherfield Sr.
– Toe
P.J. Locke
– Neck
Talanoa Hufanga
– Chest
Bo Nix
– Ankle
Troy Franklin
– Hamstring
Pat Bryant
– Concussion
Nik Bonitto
– Foot
Devaughn Vele
– Hip
Marvin Mims Jr.
– Thigh
Michael Burton
– Hamstring
Riley Moss
– Ankle
Brandon Jones
– Foot
Audric Estime
– Gameday Inactive
Blake Watson
– Undisclosed
J.K. Dobbins
– Foot
Damarri Mathis
– Knee
Tyler Badie
– Shoulder
Delarrin Turner-Yell
– Knee
JL Skinner
– Quad
Reese Taylor
– Gameday Inactive
RJ Harvey
– Ribs
Jaleel McLaughlin
– Gameday Inactive
Justin Strnad
– Foot
Drew Sanders
– Foot
Sam Franklin Jr.
– Illness
Nate Adkins
– Ankle
Garret Wallow
– Hamstring
Karene Reid
– Hamstring
Alex Singleton
– Thumb
Que Robinson
– Gameday Inactive
Jonah Elliss
– Hamstring
Andrew Farmer
– Back
Alex Forsyth
– Ankle
Jordan Turner
– Undisclosed
Dre Greenlaw
– Quad
Luke Wattenberg
– Ankle
Nick Gargiulo
– Knee
Mike McGlinchey
– Ankle/Foot
Xavier Truss
– Gameday Inactive
Frank Crum
– Gameday Inactive
Ben Powers
– Bicep
Kristian Williams
– Undisclosed
Quinn Meinerz
– Illness
Matt Peart
– Knee
Caleb Lohner
– Gameday Inactive
Lucas Krull
– Gameday Inactive
A.T. Perry
– Undisclosed
Matt Henningsen
– Achilles
Dondrea Tillman
– Hamstring
D.J. Jones
– Shoulder
Jordan Jackson
– Gameday Inactive
Sai'vion Jones
– Gameday Inactive
Malcolm Roach
– Calf
John Franklin-Myers
– Knee
Zach Allen
– Calf
Current Betting Odds
Spread: Broncos favored at 2.5
Total (Over/Under): 45.5
Moneyline Odds: Chargers -149 , Broncos +126
Recent Matches
Chargers
Broncos
Date
Vs
Result
Score
09/15/2025
Raiders
win
9 :
20
09/05/2025
Chiefs
win
27
: 21
08/23/2025
49ers
loss
30 :
23
08/16/2025
Rams
loss
23 :
22
08/10/2025
Saints
win
27
: 13
07/31/2025
Lions
win
7 :
34
01/11/2025
Texans
loss
32 :
12
01/05/2025
Raiders
win
20 :
34
12/28/2024
Patriots
win
7 :
40
12/19/2024
Broncos
win
34
: 27
W - 7
L - 3
Date
Vs
Result
Score
09/14/2025
Colts
loss
29 :
28
09/07/2025
Titans
win
20
: 12
08/23/2025
Saints
win
19 :
28
08/16/2025
Cardinals
win
27
: 7
08/09/2025
49ers
win
9 :
30
01/12/2025
Bills
loss
31 :
7
01/05/2025
Chiefs
win
38
: 0
12/28/2024
Bengals
loss
30 :
24
12/19/2024
Chargers
loss
34 :
27
12/15/2024
Colts
win
31
: 13
W - 6
L - 4
Who Wins: our Prediction
Based on statistical analysis, we see the Chargers at a win probability of 43%, while the Broncos have a propability of 57% to win.
21+ and present in VA. Gambling Problem? Call 1-800-GAMBLER.
This site is using
Cloudflare
and adheres to the
Google Safe Browsing Program. We adapted
Google's Privacy Guidelines
to keep your data safe at all times.
BetMGM Sports Promo
Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win
Gambling problem? Call 1-800-GAMBLER or 1-800-MY-RESET (Available in the US) 877-8-HOPENY or text HOPENY (467369) (NY) 1-800-327-5050 (MA), 1-800-BETS-OFF (IA), 1-800-981-0023 (PR). 21+ only. Please Gamble Responsibly. See BetMGM.com for Terms. First Bet Offer for new customers only (if applicable). Subject to eligibility requirements. Bonus bets are non-withdrawable. In partnership with Kansas Crossing Casino and Hotel. Promotional offers not available in Mississippi, New York, Ontario, or Puerto Rico.