Panthers vs Cowboys is scheduled for Sunday, October 12, 2025 at 1:00 pm ET. Point Spread: Panthers ; O/U: 46.5 ML: Cowboys +136, Panthers -161. Lines are available across major sportsbetting sites.
Money Line+145-148
Spread
3.0
-102
-3.0
+100
Over/Under
-105
Matchup Overview
Teams: Panthers vs Cowboys
Date: Sunday, October 12, 2025
Time: 01:00 pm ET
Venue: Bank of America Stadium
Where To Watch Panthers vs Cowboys on Sunday
Watch the full match on FOX.
Injuries
Panthers
Cowboys
Krys Barnes
– Gameday Inactive
Ja'Tavion Sanders
– Ankle
Mike Jackson
– Ribs
Tetairoa McMillan
– Hamstring
Rico Dowdle
– Quad
Sam Martin
– Undisclosed
Tre'von Moehrig
– Suspension
Jaycee Horn
– Thumb
Bryce Young
– Ankle
Hunter Renfrow
– Rib
Andy Dalton
– Elbow
Jimmy Horn Jr.
– Shoulder
Xavier Legette
– Hamstring
Jalen Coker
– Quad
Adam Thielen
– Gameday Inactive
Nick Scott
– Groin
Lathan Ransom
– Hand
Jonathon Brooks
– Knee
Chau Smith-Wade
– Chest
Akayleb Evans
– Illness
Chuba Hubbard
– Calf
Corey Thornton
– Leg
Trevin Wallace
– Shoulder
Princely Umanmielen
– Shoulder
Demani Richardson
– Gameday Inactive
Trevian Thomas
– Gameday Inactive
Tyler Mabry
– Undisclosed
Robert Hunt
– Foot
Claudin Cherelus
– Concussion
Cam Jackson
– Gameday Inactive
Christian Rozeboom
– Hip/Hamstring
Jarrett Kingston
– Gameday Inactive
Chandler Zavala
– Knee
Austin Corbett
– Knee
Cade Mays
– Knee
Ja'Tyre Carter
– Undisclosed
Damien Lewis
– Shoulder
Brady Christensen
– Achilles
Taylor Moton
– Elbow
Sam Roberts
– Gameday Inactive
Jared Harrison-Hunte
– Gameday Inactive
Yosh Nijman
– Gameday Inactive
Popo Aumavae
– Achilles
Ikem Ekwonu
– Illness
Tommy Tremble
– Undisclosed
David Moore
– Elbow
Mitchell Evans
– Hamstring
James Mitchell
– Gameday Inactive
Brycen Tremayne
– Quadricep
Patrick Jones II
– Ankle
Tershawn Wharton
– Hamstring
LaBryan Ray
– Undisclosed
A'Shawn Robinson
– Groin
Derrick Brown
– Knee
Jaden Crumedy
– Gameday Inactive
Bobby Brown III
– Hamstring
D.J. Wonnum
– Hip
Shy Tuttle
– Gameday Inactive
Geron Christian
– Gameday Inactive
Matt Waletzko
– Ankle
DeMarvion Overshown
– Knee
Jalen Tolbert
– Gameday Inactive
Juanyeh Thomas
– Migraine
George Pickens
– Calf/Knee
Dak Prescott
– Hip
Bryan Anger
– Illness
Donovan Wilson
– Neck
Trevon Diggs
– Knee
KaVontae Turpin
– Shoulder
Joe Milton III
– Personal
Micah Parsons
– Back
Dante Fowler Jr.
– Shoulder
Markquese Bell
– Lower Body
Damone Clark
– Gameday Inactive
Ryan Flournoy
– Knee
Caelen Carson
– Knee
Buddy Johnson
– Gameday Inactive
DaRon Bland
– Foot
Miles Sanders
– Shoulder
Shavon Revel Jr.
– Undisclosed
Malik Hooker
– Toe
R.Rochell
– Ankle
Josh Butler
– Knee
J.Williams
– Neck
Jaydon Blue
– Ankle
Bruce Harmon
– Knee
Christian Matthew
– Undisclosed
Phil Mafah
– Shoulder
Alijah Clark
– Ribs
Hunter Luepke
– Hip
Kemon Hall
– Suspension
Darius Harris
– Undisclosed
Zion Childress
– Gameday Inactive
John Stephens Jr.
– Undisclosed
Shemar James
– Gameday Inactive
Tyler Booker
– Ankle
James Houston
– Knee
Sam Williams
– Shoulder
Cooper Beebe
– Ankle
Jack Sanborn
– Concussion
Mazi Smith
– Gameday Inactive
Kenneth Murray Jr.
– Knee
Tyler Guyton
– Knee
Dakoda Shepley
– Undisclosed
Rob Jones
– Neck
T.J. Bass
– Thumb
Ajani Cornelius
– Gameday Inactive
Nate Thomas
– Shoulder
Tyler Smith
– Knee
Hakeem Adeniji
– Gameday Inactive
Asim Richards
– Ankle
Terence Steele
– Migraine
P.Campbell
– Undisclosed
Jonathan Mingo
– Knee
Jalen Brooks
– Undisclosed
Luke Schoonmaker
– Concussion
Jake Ferguson
– Calf
CeeDee Lamb
– Ankle
Brevyn Spann-Ford
– Ankle
Solomon Thomas
– Calf
Tyrus Wheat
– Gameday Inactive
Jay Toia
– Gameday Inactive
Marshawn Kneeland
– Ankle
Osa Odighizuwa
– Elbow
Payton Turner
– Ribs
Perrion Winfrey
– Back
Current Betting Odds
Spread: Panthers favored at 3
Total (Over/Under): 46.5
Moneyline Odds: Panthers +136 , Cowboys -161
Recent Matches
Panthers
Cowboys
Date
Vs
Result
Score
10/05/2025
Dolphins
win
27
: 24
09/28/2025
Patriots
loss
42 :
13
09/21/2025
Falcons
win
30
: 0
09/14/2025
Cardinals
loss
27 :
22
09/07/2025
Jaguars
loss
26 :
10
08/21/2025
Steelers
loss
10
: 19
08/16/2025
Texans
loss
20 :
3
08/08/2025
Browns
loss
10
: 30
01/05/2025
Falcons
win
38 :
44
12/29/2024
Buccaneers
loss
48 :
14
W - 3
L - 7
Date
Vs
Result
Score
10/05/2025
Jets
win
22 :
37
09/28/2025
Packers
draw
40
: 40
09/21/2025
Bears
loss
31 :
14
09/14/2025
Giants
win
40
: 37
09/04/2025
Eagles
loss
24 :
20
08/22/2025
Falcons
win
31
: 13
08/16/2025
Ravens
loss
13
: 31
08/09/2025
Rams
loss
31 :
21
01/05/2025
Commanders
loss
19
: 23
12/29/2024
Eagles
loss
41 :
7
W - 3
D - 1
L - 6
Who Wins: our Prediction
Based on statistical analysis, we see the Panthers at a win probability of 59%, while the Cowboys have a propability of 41% to win.
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