Panthers vs Patriots NFL Week 4 – Match Preview & Live Updates Sunday, September 28, 2025

National Football League
Patriots
Home
28/09/2025
1:00pm
Panthers
Away

Patriots vs. Panthers: Detailed Breakdown

For Patriots at Panthers on Sunday, September 28, 2025, sportsbooks post Point Spread Panthers with O/U 42.5 ML: Panthers -245, Patriots +203 appears on boards. Kickoff is 1:00 pm ET. Lines are live at books.

Money Line -240 Fanatics +220 FanDuel
Spread -5.5 -110 FanDuel 5.5 -108 DraftKings
Over/Under -105 BetMGM FanDuel

Matchup Overview

  • Teams: Patriots vs Panthers
  • Date: Sunday, September 28, 2025
  • Time: 01:00 pm ET
  • Venue: Gillette Stadium

Where To Watch Patriots vs Panthers on Sunday

Watch the full match on FOX.

Injuries

Patriots
Panthers
Yasir Durant
– Undisclosed
Christian Gonzalez
– Concussion
Ja'Lynn Polk
– Shoulder
Harold Landry III
– Foot
DeMario Douglas
– Hamstring
Antonio Gibson
– Knee
Jabrill Peppers
– Quadricep
Carlton Davis III
– Achilles
Stefon Diggs
– Knee
Kayshon Boutte
– Shoulder
Drake Maye
– Right Shoulder
Mack Hollins
– Hand
Robert Spillane
– Hand
Marte Mapu
– Neck
Kobee Minor
– Gameday Inactive
Jaylinn Hawkins
– Hamstring
Marcus Epps
– Shoulder
Kyle Dugger
– Knee
Marcus Jones
– Elbow
Terrell Jennings
– Head
Marcellas Dial Jr.
– ACL
Alex Austin
– Undisclosed
Jeremiah Webb
– Undisclosed
Craig Woodson
– Ankle
TreVeyon Henderson
– Shoulder
Anfernee Jennings
– Knee
Lan Larison
– Undisclosed
Rhamondre Stevenson
– Toe
Brenden Schooler
– Ankle
Bradyn Swinson
– Gameday Inactive
K'Lavon Chaisson
– Knee
Brock Lampe
– Undisclosed
Jahlani Tavai
– Calf
Jack Gibbens
– Hamstring
Marcus Bryant
– Gameday Inactive
Christian Elliss
– Shoulder
Jared Wilson
– Thigh
Vederian Lowe
– Undisclosed
Layden Robinson
– Undisclosed
Garrett Bradbury
– Illness
Will Campbell
– Ankle
Isaiah Iton
– Hip
Caedan Wallace
– Gameday Inactive
Mike Onwenu
– Shoulder
Demontrey Jacobs
– Gameday Inactive
Morgan Moses
– Knee
Austin Hooper
– Undisclosed
CJ Dippre
– Illness
Kendrick Bourne
– Rib
Hunter Henry
– Knee
Efton Chism III
– Knee
Jack Westover
– Hamstring
Christian Barmore
– Personal
Elijah Ponder
– Gameday Inactive
Joshua Farmer
– Ankle
Jaquelin Roy
– Undisclosed
Khyiris Tonga
– Knee
M.Williams
– Ankle
Keion White
– Illness
Krys Barnes
– Gameday Inactive
Ja'Tavion Sanders
– Ankle
Mike Jackson
– Ribs
Tetairoa McMillan
– Hamstring
Rico Dowdle
– Quad
Sam Martin
– Undisclosed
Tre'von Moehrig
– Suspension
Jaycee Horn
– Thumb
Bryce Young
– Ankle
Hunter Renfrow
– Rib
Andy Dalton
– Elbow
Jimmy Horn Jr.
– Shoulder
Xavier Legette
– Hamstring
Jalen Coker
– Quad
Adam Thielen
– Gameday Inactive
Nick Scott
– Groin
Lathan Ransom
– Hand
Jonathon Brooks
– Knee
Chau Smith-Wade
– Chest
Akayleb Evans
– Illness
Chuba Hubbard
– Calf
Corey Thornton
– Leg
Trevin Wallace
– Shoulder
Princely Umanmielen
– Shoulder
Demani Richardson
– Gameday Inactive
Trevian Thomas
– Gameday Inactive
Tyler Mabry
– Undisclosed
Robert Hunt
– Foot
Claudin Cherelus
– Concussion
Cam Jackson
– Gameday Inactive
Christian Rozeboom
– Hip/Hamstring
Jarrett Kingston
– Gameday Inactive
Chandler Zavala
– Knee
Austin Corbett
– Knee
Cade Mays
– Knee
Ja'Tyre Carter
– Undisclosed
Damien Lewis
– Shoulder
Brady Christensen
– Achilles
Taylor Moton
– Elbow
Sam Roberts
– Gameday Inactive
Jared Harrison-Hunte
– Gameday Inactive
Yosh Nijman
– Gameday Inactive
Popo Aumavae
– Achilles
Ikem Ekwonu
– Illness
Tommy Tremble
– Undisclosed
David Moore
– Elbow
Mitchell Evans
– Hamstring
James Mitchell
– Gameday Inactive
Brycen Tremayne
– Quadricep
Patrick Jones II
– Ankle
Tershawn Wharton
– Hamstring
LaBryan Ray
– Undisclosed
A'Shawn Robinson
– Groin
Derrick Brown
– Knee
Jaden Crumedy
– Gameday Inactive
Bobby Brown III
– Hamstring
D.J. Wonnum
– Hip
Shy Tuttle
– Gameday Inactive

Current Betting Odds

  • Spread: Panthers favored at 5.5
  • Total (Over/Under): 42.5
  • Moneyline Odds: Patriots -245 , Panthers +203

Recent Matches

Patriots
Panthers
Date Vs Result Score
09/21/2025 Steelers loss 14 : 21
09/14/2025 Dolphins win 27 : 33
09/07/2025 Raiders loss 13 : 20
08/21/2025 Giants loss 42 : 10
08/16/2025 Vikings win 12 : 20
08/08/2025 Commanders win 48 : 18
01/05/2025 Bills win 23 : 16
12/28/2024 Chargers loss 7 : 40
12/22/2024 Bills loss 24 : 21
12/15/2024 Cardinals loss 30 : 17
W - 4
L - 6
Date Vs Result Score
09/21/2025 Falcons win 30 : 0
09/14/2025 Cardinals loss 27 : 22
09/07/2025 Jaguars loss 26 : 10
08/21/2025 Steelers loss 10 : 19
08/16/2025 Texans loss 20 : 3
08/08/2025 Browns loss 10 : 30
01/05/2025 Falcons win 38 : 44
12/29/2024 Buccaneers loss 48 : 14
12/22/2024 Cardinals win 36 : 30
12/15/2024 Cowboys loss 14 : 30
W - 3
L - 7

Who Wins: our Prediction

Based on statistical analysis, we see the Patriots at a win probability of 32%, while the Panthers have a propability of 68% to win.

Find the best Futures for Patriots vs Panthers

Statistics

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Money Line -116 FanDuel +100 BetMGM
Spread -1.5 -105 DraftKings 1.0 -110 BetMGM
Over/Under -102 FanDuel DraftKings
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Spread 3.5 -102 FanDuel -3.5 -105 BetMGM
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Money Line +135 BetMGM -150 Fanatics
Spread 2.5 -102 FanDuel -3.0 -102 BetMGM
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Money Line -1299 Fanatics +950 DraftKings
Spread -14.5 +100 FanDuel 14.0 -105 Fanatics
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Money Line -375 BetMGM +320 DraftKings
Spread -7.5 -105 BetMGM 7.5 -105 BetMGM
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Spread -3.5 -105 DraftKings 3.5 -110 Fanatics
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Spread 4.5 -114 FanDuel -4.5 -105 DraftKings
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Money Line +370 DraftKings -450 Fanatics
Spread 8.5 -105 FanDuel -8.5 -108 DraftKings
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Money Line +300 BetMGM -350 FanDuel
Spread 7.0 -102 FanDuel -7.5 +100 DraftKings
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Spread 13.5 -106 FanDuel -13.5 -105 DraftKings
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Money Line -115 Fanatics +102 FanDuel
Spread -1.5 -105 DraftKings 1.5 -110 FanDuel
Over/Under -110 FanDuel DraftKings
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