For Patriots at Panthers on Sunday, September 28, 2025, sportsbooks post Point Spread Panthers with O/U 42.5 ML: Panthers -245, Patriots +203 appears on boards. Kickoff is 1:00 pm ET. Lines are live at books.
Money Line-240+220
Spread
-5.5
-110
5.5
-108
Over/Under
-105
Matchup Overview
Teams: Patriots vs Panthers
Date: Sunday, September 28, 2025
Time: 01:00 pm ET
Venue: Gillette Stadium
Where To Watch Patriots vs Panthers on Sunday
Watch the full match on FOX.
Injuries
Patriots
Panthers
Yasir Durant
– Undisclosed
Christian Gonzalez
– Concussion
Ja'Lynn Polk
– Shoulder
Harold Landry III
– Foot
DeMario Douglas
– Hamstring
Antonio Gibson
– Knee
Jabrill Peppers
– Quadricep
Carlton Davis III
– Achilles
Stefon Diggs
– Knee
Kayshon Boutte
– Shoulder
Drake Maye
– Right Shoulder
Mack Hollins
– Hand
Robert Spillane
– Hand
Marte Mapu
– Neck
Kobee Minor
– Gameday Inactive
Jaylinn Hawkins
– Hamstring
Marcus Epps
– Shoulder
Kyle Dugger
– Knee
Marcus Jones
– Elbow
Terrell Jennings
– Undisclosed
Marcellas Dial Jr.
– ACL
Alex Austin
– Undisclosed
Jeremiah Webb
– Undisclosed
DJ James
– Undisclosed
Craig Woodson
– Ankle
TreVeyon Henderson
– Shoulder
Anfernee Jennings
– Knee
Lan Larison
– Undisclosed
Rhamondre Stevenson
– Toe
Brenden Schooler
– Undisclosed
Bradyn Swinson
– Gameday Inactive
K'Lavon Chaisson
– Knee
Brock Lampe
– Undisclosed
Jahlani Tavai
– Calf
Jack Gibbens
– Hamstring
Marcus Bryant
– Gameday Inactive
Christian Elliss
– Shoulder
Jared Wilson
– Thigh
Vederian Lowe
– Undisclosed
Layden Robinson
– Undisclosed
Garrett Bradbury
– Illness
Will Campbell
– Ankle
Isaiah Iton
– Hip
Caedan Wallace
– Gameday Inactive
Mike Onwenu
– Shoulder
Demontrey Jacobs
– Gameday Inactive
Morgan Moses
– Knee
Gee Scott Jr.
– Undisclosed
Austin Hooper
– Undisclosed
CJ Dippre
– Illness
Kendrick Bourne
– Rib
Hunter Henry
– Knee
Efton Chism III
– Knee
Jack Westover
– Hamstring
Christian Barmore
– Personal
Elijah Ponder
– Gameday Inactive
Joshua Farmer
– Ankle
Jaquelin Roy
– Undisclosed
Khyiris Tonga
– Knee
M.Williams
– Ankle
Keion White
– Illness
Krys Barnes
– Gameday Inactive
Ja'Tavion Sanders
– Ankle
Mike Jackson
– Ribs
Tetairoa McMillan
– Hamstring
Rico Dowdle
– Quad
Sam Martin
– Undisclosed
Tre'von Moehrig
– Suspension
Jaycee Horn
– Thumb
Bryce Young
– Ankle
Nic Scourton
– Knee
Hunter Renfrow
– Rib
Andy Dalton
– Elbow
Jimmy Horn Jr.
– Shoulder
Xavier Legette
– Hamstring
Jalen Coker
– Quad
Adam Thielen
– Gameday Inactive
Nick Scott
– Groin
Lathan Ransom
– Hand
Jonathon Brooks
– Knee
Chau Smith-Wade
– Chest
Akayleb Evans
– Illness
Chuba Hubbard
– Calf
Corey Thornton
– Leg
Trevin Wallace
– Shoulder
Princely Umanmielen
– Shoulder
Demani Richardson
– Gameday Inactive
Trevian Thomas
– Gameday Inactive
Tyler Mabry
– Undisclosed
Robert Hunt
– Foot
Claudin Cherelus
– Concussion
Cam Jackson
– Gameday Inactive
Christian Rozeboom
– Hip/Hamstring
Jarrett Kingston
– Gameday Inactive
Chandler Zavala
– Knee
Austin Corbett
– Knee
Cade Mays
– Knee
Ja'Tyre Carter
– Undisclosed
Damien Lewis
– Shoulder
Brady Christensen
– Achilles
Taylor Moton
– Lung
Sam Roberts
– Gameday Inactive
Jared Harrison-Hunte
– Gameday Inactive
Yosh Nijman
– Gameday Inactive
Popo Aumavae
– Achilles
Ikem Ekwonu
– Illness
Tommy Tremble
– Undisclosed
David Moore
– Elbow
Mitchell Evans
– Hamstring
James Mitchell
– Gameday Inactive
Brycen Tremayne
– Quadricep
Patrick Jones II
– Ankle
Tershawn Wharton
– Neck
LaBryan Ray
– Undisclosed
A'Shawn Robinson
– Groin
Derrick Brown
– Knee
Jaden Crumedy
– Gameday Inactive
Bobby Brown III
– Hamstring
D.J. Wonnum
– Hip
Shy Tuttle
– Gameday Inactive
Current Betting Odds
Spread: Panthers favored at 5.5
Total (Over/Under): 42.5
Moneyline Odds: Patriots -245 , Panthers +203
Recent Matches
Patriots
Panthers
Date
Vs
Result
Score
09/21/2025
Steelers
loss
14
: 21
09/14/2025
Dolphins
win
27 :
33
09/07/2025
Raiders
loss
13
: 20
08/21/2025
Giants
loss
42 :
10
08/16/2025
Vikings
win
12 :
20
08/08/2025
Commanders
win
48
: 18
01/05/2025
Bills
win
23
: 16
12/28/2024
Chargers
loss
7
: 40
12/22/2024
Bills
loss
24 :
21
12/15/2024
Cardinals
loss
30 :
17
W - 4
L - 6
Date
Vs
Result
Score
09/21/2025
Falcons
win
30
: 0
09/14/2025
Cardinals
loss
27 :
22
09/07/2025
Jaguars
loss
26 :
10
08/21/2025
Steelers
loss
10
: 19
08/16/2025
Texans
loss
20 :
3
08/08/2025
Browns
loss
10
: 30
01/05/2025
Falcons
win
38 :
44
12/29/2024
Buccaneers
loss
48 :
14
12/22/2024
Cardinals
win
36
: 30
12/15/2024
Cowboys
loss
14
: 30
W - 3
L - 7
Who Wins: our Prediction
Based on statistical analysis, we see the Patriots at a win probability of 32%, while the Panthers have a propability of 68% to win.
21+ and present in VA. Gambling Problem? Call 1-800-GAMBLER.
This site is using
Cloudflare
and adheres to the
Google Safe Browsing Program. We adapted
Google's Privacy Guidelines
to keep your data safe at all times.
BetMGM Sports Promo
Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win
Gambling problem? Call 1-800-GAMBLER or 1-800-MY-RESET (Available in the US) 877-8-HOPENY or text HOPENY (467369) (NY) 1-800-327-5050 (MA), 1-800-BETS-OFF (IA), 1-800-981-0023 (PR). 21+ only. Please Gamble Responsibly. See BetMGM.com for Terms. First Bet Offer for new customers only (if applicable). Subject to eligibility requirements. Bonus bets are non-withdrawable. In partnership with Kansas Crossing Casino and Hotel. Promotional offers not available in Mississippi, New York, Ontario, or Puerto Rico.
Steelers
Dolphins
Raiders
Giants
Vikings
Commanders
Bills
Chargers
Cardinals
Falcons
Jaguars
Texans
Browns
Buccaneers
Cowboys
Daily picks from betting experts on odds boosts and casino promos
