For Patriots at Bills on Sunday, December 14, 2025, sportsbooks post Point Spread Patriots with O/U 49.5 ML: Bills +115, Patriots -135 appears on boards. Kickoff is 1:00 pm ET. Lines are live at books.
Money Line+118-134
Spread
2.5
-110
-2.5
-105
Over/Under
-108
Matchup Overview
Teams: Patriots vs Bills
Date: Sunday, December 14, 2025
Time: 01:00 pm ET
Venue: Gillette Stadium
Where To Watch Patriots vs Bills on Sunday
Watch the full match on CBS.
Injuries
Patriots
Bills
Yasir Durant
– Undisclosed
Christian Gonzalez
– Concussion
Ja'Lynn Polk
– Shoulder
Harold Landry III
– Foot
DeMario Douglas
– Hamstring
Antonio Gibson
– Knee
Jabrill Peppers
– Quadricep
Carlton Davis III
– Achilles
Stefon Diggs
– Knee
Kayshon Boutte
– Shoulder
Drake Maye
– Right Shoulder
Mack Hollins
– Hand
Robert Spillane
– Hand
Marte Mapu
– Neck
Kobee Minor
– Gameday Inactive
Jaylinn Hawkins
– Hamstring
Marcus Epps
– Shoulder
Kyle Dugger
– Knee
Marcus Jones
– Elbow
Terrell Jennings
– Undisclosed
Marcellas Dial Jr.
– ACL
Alex Austin
– Undisclosed
Jeremiah Webb
– Undisclosed
DJ James
– Undisclosed
Craig Woodson
– Ankle
TreVeyon Henderson
– Shoulder
Anfernee Jennings
– Knee
Lan Larison
– Undisclosed
Rhamondre Stevenson
– Toe
Brenden Schooler
– Undisclosed
Bradyn Swinson
– Gameday Inactive
K'Lavon Chaisson
– Knee
Brock Lampe
– Undisclosed
Jahlani Tavai
– Calf
Jack Gibbens
– Hamstring
Marcus Bryant
– Gameday Inactive
Christian Elliss
– Shoulder
Jared Wilson
– Thigh
Vederian Lowe
– Undisclosed
Layden Robinson
– Undisclosed
Garrett Bradbury
– Illness
Will Campbell
– Ankle
Isaiah Iton
– Hip
Caedan Wallace
– Gameday Inactive
Mike Onwenu
– Shoulder
Demontrey Jacobs
– Gameday Inactive
Morgan Moses
– Knee
Gee Scott Jr.
– Undisclosed
Austin Hooper
– Undisclosed
CJ Dippre
– Illness
Kendrick Bourne
– Rib
Hunter Henry
– Knee
Efton Chism III
– Knee
Jack Westover
– Hamstring
Christian Barmore
– Personal
Elijah Ponder
– Gameday Inactive
Joshua Farmer
– Ankle
Jaquelin Roy
– Undisclosed
Khyiris Tonga
– Knee
M.Williams
– Ankle
Keion White
– Illness
Hayden Harris
– Hamstring
Keon Coleman
– Groin
Curtis Samuel
– Elbow
Tyler Bass
– Left Hip/Groin
Damar Hamlin
– Pectoral
James Cook
– Hamstring
Joshua Palmer
– Ankle
Taron Johnson
– Groin
Terrel Bernard
– Hamstring
Taylor Rapp
– Nose
Khalil Shakir
– Ankle
Mitchell Trubisky
– Illness
Jalen Virgil
– Undisclosed
Mike White
– Gameday Inactive
Josh Allen
– Right Elbow
Elijah Moore
– Personal
Darrynton Evans
– Undisclosed
Ray Davis
– Illness
Cole Bishop
– Cramping
Daequan Hardy
– Undisclosed
Ty Johnson
– Ankle
Tre'Davious White
– Leg
Darrick Forrest
– Undisclosed
Brandon Codrington
– Knee
Wande Owens
– Undisclosed
Maxwell Hairston
– Knee
Te'Cory Couch
– Hamstring
Jordan Hancock
– Shoulder
Cam Lewis
– Shoulder
Reggie Gilliam
– Knee
Dorian Williams
– Knee
Dorian Strong
– Neck
Shaq Thompson
– Hamstring/Hand
Ja'Marcus Ingram
– Gameday Inactive
Christian Benford
– Groin
Greg Rousseau
– Knee
Kendrick Green
– Undisclosed
Baylon Spector
– Undisclosed
Michael Hoecht
– Suspension
A.J. Epenesa
– Pectoral
Matt Milano
– Pectoral
Sedrick Van Pran-Granger
– Undisclosed
Connor McGovern
– Hamstring
Tylan Grable
– Undisclosed
Reid Ferguson
– Neck
Alec Anderson
– Knee
Marcus Harris
– Knee
Dion Dawkins
– Thumb
Chase Lundt
– Gameday Inactive
Spencer Brown
– Undisclosed
Tyrell Shavers
– Knee
Kaden Prather
– Hamstring
Jackson Hawes
– Ankle
Dalton Kincaid
– Hamstring
Dawson Knox
– Hip
DeWayne Carter
– Achilles
Ed Oliver
– Bicep
DaQuan Jones
– Calf
Landon Jackson
– Gameday Inactive
Deone Walker
– Ilness
Joey Bosa
– Hamstring
T.J. Sanders
– Knee
Larry Ogunjobi
– Gameday Inactive
Current Betting Odds
Spread: Patriots favored at 2.5
Total (Over/Under): 49.5
Moneyline Odds: Patriots +115 , Bills -135
Recent Matches
Patriots
Bills
Date
Vs
Result
Score
12/01/2025
Giants
win
33
: 15
11/23/2025
Bengals
win
20 :
26
11/13/2025
Jets
win
27
: 14
11/09/2025
Buccaneers
win
23 :
28
11/02/2025
Falcons
win
24
: 23
10/26/2025
Browns
win
32
: 13
10/19/2025
Titans
win
13 :
31
10/12/2025
Saints
win
19 :
25
10/05/2025
Bills
win
20 :
23
09/28/2025
Panthers
win
42
: 13
W - 10
Date
Vs
Result
Score
12/07/2025
Bengals
win
39
: 34
11/30/2025
Steelers
win
7 :
26
11/20/2025
Texans
loss
23 :
19
11/16/2025
Buccaneers
win
44
: 32
11/09/2025
Dolphins
loss
30 :
13
11/02/2025
Chiefs
win
28
: 21
10/26/2025
Panthers
win
9 :
40
10/13/2025
Falcons
loss
24 :
14
10/05/2025
Patriots
loss
20
: 23
09/28/2025
Saints
win
31
: 19
W - 6
L - 4
Who Wins: our Prediction
Based on statistical analysis, we see the Patriots at a win probability of 55%, while the Bills have a propability of 45% to win.
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