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    Browns vs Bills NFL Week 16 – Match Preview & Live Updates Sunday, December 21, 2025

    National Football League
    Browns
    Home
    21/12/2025
    1:00pm
    Bills
    Away
    Where To Watch Injuries Recent Matches Predicted Winner Futures Statistics

    Browns vs. Bills: Detailed Breakdown

    Bills host Browns this Sunday at Huntington Bank Field. Books show point spread (Browns ) and total sitting at 40.5. M/L: Bills +444, Browns -613. Numbers reflect current sportsbook listings at the time of writing.

    Money Line +455 DraftKings -592 FanDuel
    Spread 10.0 -105 BetMGM -10.5 -104 FanDuel
    Over/Under -110 BetMGM DraftKings

    Matchup Overview

    • Teams: Browns vs Bills
    • Date: Sunday, December 21, 2025
    • Time: 01:00 pm ET
    • Venue: Huntington Bank Field

    Where To Watch Browns vs Bills on Sunday

    Watch the full match on CBS.

    Injuries

    Browns
    Bills
    Greg Newsome II
    – Shoulder
    Martin Emerson Jr.
    – Achilles
    DeAndre Carter
    – Knee
    Jerry Jeudy
    – Knee
    Deshaun Watson
    – Achilles
    Dillon Gabriel
    – Concussion
    Jeremiah Owusu-Koramoah
    – Neck
    K.Pickett
    – Hamstring
    Grant Delpit
    – Back
    Quinshon Judkins
    – Not Injury Related
    Shedeur Sanders
    – Gameday Inactive
    Corey Bojorquez
    – Right Ankle
    Joe Flacco
    – Right Shoulder/Right Finger
    Jerome Baker
    – Achilles
    David Bell
    – Undisclosed
    Cedric Tillman
    – Thumb
    Pierre Strong Jr.
    – Undisclosed
    Denzel Ward
    – Shoulder
    Dylan Sampson
    – Calf
    Damontae Kazee
    – Gameday Inactive
    Myles Harden
    – Ankle
    Rayshawn Jenkins
    – Wrist
    Cameron Mitchell
    – Gameday Inactive
    Devin Bush
    – Foot
    Cade McDonald
    – Undisclosed
    Jerome Ford
    – Shoulder
    Dom Jones
    – Knee
    Nathaniel Watson
    – Biceps
    Easton Mascarenas-Arnold
    – Achilles
    Mohamoud Diabate
    – Quad
    Anthony Kendall
    – Undisclosed
    Andre Szmyt
    – Left Calf
    Carson Schwesinger
    – Ankle
    Mike Hall Jr.
    – Undisclosed
    Julian Okwara
    – Undisclosed
    Ethan Pocic
    – Knee
    Isaiah McGuire
    – Knee
    Winston Reid
    – Back
    Adin Huntington
    – Concussion
    Zak Zinter
    – Gameday Inactive
    Cornelius Lucas
    – Ankle
    Teven Jenkins
    – Shoulder
    Joel Bitonio
    – Back
    Wyatt Teller
    – Calf
    Jack Conklin
    – Elbow
    Dawand Jones
    – Knee
    Jamari Thrash
    – Gameday Inactive
    Brenden Bates
    – Gameday Inactive
    Gage Larvadain
    – Gameday Inactive
    David Njoku
    – Knee
    Blake Whiteheart
    – Knee
    Harold Fannin Jr.
    – Hamstring
    Joe Tryon-Shoyinka
    – Gameday Inactive
    Alex Wright
    – Quad
    Sam Kamara
    – Gameday Inactive
    Shelby Harris
    – Illness
    Mason Graham
    – Shoulder
    Myles Garrett
    – Ankle
    Maliek Collins
    – Quadricep
    Hayden Harris
    – Hamstring
    Keon Coleman
    – Groin
    Curtis Samuel
    – Elbow
    Tyler Bass
    – Left Hip/Groin
    Damar Hamlin
    – Pectoral
    James Cook
    – Hamstring
    Joshua Palmer
    – Ankle
    Taron Johnson
    – Groin
    Terrel Bernard
    – Hamstring
    Taylor Rapp
    – Nose
    Khalil Shakir
    – Ankle
    Mitchell Trubisky
    – Illness
    Jalen Virgil
    – Undisclosed
    Mike White
    – Gameday Inactive
    Josh Allen
    – Right Elbow
    Elijah Moore
    – Personal
    Darrynton Evans
    – Undisclosed
    Ray Davis
    – Illness
    Cole Bishop
    – Cramping
    Daequan Hardy
    – Undisclosed
    Ty Johnson
    – Ankle
    Tre'Davious White
    – Leg
    Darrick Forrest
    – Undisclosed
    Brandon Codrington
    – Knee
    Wande Owens
    – Undisclosed
    Maxwell Hairston
    – Knee
    Te'Cory Couch
    – Hamstring
    Jordan Hancock
    – Shoulder
    Cam Lewis
    – Shoulder
    Reggie Gilliam
    – Knee
    Dorian Williams
    – Knee
    Dorian Strong
    – Neck
    Shaq Thompson
    – Hamstring/Hand
    Ja'Marcus Ingram
    – Gameday Inactive
    Christian Benford
    – Groin
    Greg Rousseau
    – Knee
    Kendrick Green
    – Undisclosed
    Baylon Spector
    – Undisclosed
    Michael Hoecht
    – Suspension
    A.J. Epenesa
    – Pectoral
    Matt Milano
    – Pectoral
    Sedrick Van Pran-Granger
    – Undisclosed
    Connor McGovern
    – Hamstring
    Tylan Grable
    – Undisclosed
    Reid Ferguson
    – Neck
    Alec Anderson
    – Knee
    Marcus Harris
    – Knee
    Dion Dawkins
    – Thumb
    Chase Lundt
    – Gameday Inactive
    Spencer Brown
    – Undisclosed
    Tyrell Shavers
    – Knee
    Kaden Prather
    – Hamstring
    Jackson Hawes
    – Ankle
    Dalton Kincaid
    – Hamstring
    Dawson Knox
    – Hip
    DeWayne Carter
    – Achilles
    Ed Oliver
    – Bicep
    DaQuan Jones
    – Calf
    Landon Jackson
    – Gameday Inactive
    Deone Walker
    – Ilness
    Joey Bosa
    – Hamstring
    T.J. Sanders
    – Knee
    Larry Ogunjobi
    – Gameday Inactive

    Current Betting Odds

    • Spread: Browns favored at 10.5
    • Total (Over/Under): 40.5
    • Moneyline Odds: Browns +444 , Bills -613

    Recent Matches

    Browns
    Bills
    Date Vs Result Score
    12/14/2025 Bears loss 31 : 3
    12/07/2025 Titans loss 29 : 31
    11/30/2025 49ers loss 8 : 26
    11/23/2025 Raiders win 10 : 24
    11/16/2025 Ravens loss 16 : 23
    11/09/2025 Jets loss 27 : 20
    10/26/2025 Patriots loss 32 : 13
    10/19/2025 Dolphins win 31 : 6
    10/12/2025 Steelers loss 23 : 9
    10/05/2025 Vikings loss 17 : 21
    W - 2
    L - 8
    Date Vs Result Score
    12/14/2025 Patriots win 31 : 35
    12/07/2025 Bengals win 39 : 34
    11/30/2025 Steelers win 7 : 26
    11/20/2025 Texans loss 23 : 19
    11/16/2025 Buccaneers win 44 : 32
    11/09/2025 Dolphins loss 30 : 13
    11/02/2025 Chiefs win 28 : 21
    10/26/2025 Panthers win 9 : 40
    10/13/2025 Falcons loss 24 : 14
    10/05/2025 Patriots loss 20 : 23
    W - 6
    L - 4

    Who Wins: our Prediction

    Based on statistical analysis, we see the Browns at a win probability of 82%, while the Bills have a propability of 18% to win.

    Find the best Futures for Browns vs Bills

    Statistics

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    All Betting Tips
    Money Line -116 FanDuel +100 BetMGM
    Spread -1.5 -105 DraftKings 1.0 -110 BetMGM
    Over/Under -102 FanDuel DraftKings
    Money Line +176 FanDuel -200 BetMGM
    Spread 3.5 -102 FanDuel -3.5 -105 BetMGM
    Over/Under -108 DraftKings DraftKings
    Money Line +130 DraftKings -152 FanDuel
    Spread 3.0 -115 BetMGM -3.0 -102 DraftKings
    Over/Under -108 DraftKings DraftKings
    Money Line +455 DraftKings -592 FanDuel
    Spread 10.0 -105 BetMGM -10.5 -104 FanDuel
    Over/Under -110 BetMGM DraftKings
    Money Line -180 DraftKings +154 BetMGM
    Spread -3.5 +100 DraftKings 3.5 -115 BetMGM
    Over/Under -110 FanDuel DraftKings
    Money Line +135 BetMGM -150 Fanatics
    Spread 2.5 -102 FanDuel -3.0 -102 BetMGM
    Over/Under -108 FanDuel DraftKings
    Money Line -1299 Fanatics +950 DraftKings
    Spread -14.5 +100 FanDuel 14.0 -105 Fanatics
    Over/Under -105 Fanatics DraftKings
    Money Line -375 BetMGM +320 DraftKings
    Spread -7.5 -105 BetMGM 7.5 -105 BetMGM
    Over/Under -105 DraftKings DraftKings
    Money Line -190 BetMGM +164 DraftKings
    Spread -3.5 -105 DraftKings 3.5 -110 Fanatics
    Over/Under -105 FanDuel DraftKings
    Money Line +187.5 FanDuel -218 DraftKings
    Spread 4.5 -114 FanDuel -4.5 -105 DraftKings
    Over/Under -102 DraftKings DraftKings
    Money Line +370 DraftKings -450 Fanatics
    Spread 8.5 -105 FanDuel -8.5 -108 DraftKings
    Over/Under -108 FanDuel DraftKings
    Money Line +300 BetMGM -350 FanDuel
    Spread 7.0 -102 FanDuel -7.5 +100 DraftKings
    Over/Under -108 DraftKings DraftKings
    Money Line +810 FanDuel -1000 BetMGM
    Spread 13.5 -106 FanDuel -13.5 -105 DraftKings
    Over/Under -105 DraftKings DraftKings
    Money Line -115 Fanatics +102 FanDuel
    Spread -1.5 -105 DraftKings 1.5 -110 FanDuel
    Over/Under -110 FanDuel DraftKings
    Money Line -140 BetMGM +120 DraftKings
    Spread -2.5 -105 BetMGM 2.5 -105 DraftKings
    Over/Under -105 DraftKings DraftKings
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