On Sunday, September 27, 2026, 49ers face Cardinals. The Point Spread is Cardinals , while the Total is 48 M/L: Cardinals -433, 49ers +338 is available. Sportsbetting sites have full lines listed.
+380
8.5
-105
Watch the full match on FOX.
49ers
Cardinals
49ers
Cardinals
| Date | Vs | Result | Score |
|---|---|---|---|
| 09/20/2026 | 
Dolphins |
win | 35 : 13 |
| 09/10/2026 | 
Rams |
win | 7 : 27 |
| 08/27/2026 | 
Raiders |
win | 12 : 18 |
| 08/20/2026 | 
Chargers |
win | 17 : 41 |
| 08/13/2026 | 
Titans |
loss | 13 : 19 |
| 01/17/2026 | 
Seahawks |
loss | 41 : 6 |
| 01/11/2026 | 
Eagles |
win | 19 : 23 |
| 01/03/2026 |
Seahawks |
loss | 3 : 13 |
| 12/28/2025 | 
Bears |
win | 42 : 38 |
| 12/22/2025 | 
Colts |
win | 27 : 48 |
| Date | Vs | Result | Score |
|---|---|---|---|
| 09/20/2026 |
Seahawks |
loss | 7 : 31 |
| 09/13/2026 |
Chargers |
win | 14 : 26 |
| 08/28/2026 | 
Packers |
loss | 42 : 38 |
| 08/22/2026 | 
Cowboys |
loss | 13 : 34 |
| 08/15/2026 |
Raiders |
draw | : |
| 08/06/2026 | 
Panthers |
loss | 30 : 33 |
| 01/04/2026 |
Rams |
loss | 37 : 20 |
| 12/28/2025 | 
Bengals |
loss | 37 : 14 |
| 12/21/2025 | 
Falcons |
loss | 19 : 26 |
| 12/14/2025 | 
Texans |
loss | 40 : 20 |
Based on statistical analysis, we see the 49ers at a win probability of 22%, while the Cardinals have a propability of 78% to win.
-190
-3.5
-105
-125
-1.5
-110
-142
-2.5
-115
+260
6.5
-102
+120
2.5
-105
-375
-7.5
-105
-649
-10.5
-110
+130
2.5
-104
+295
7.0
-105
+380
8.5
-105
-120
-1.5
-108
-178
-3.5
-102
+150
3.0
-102
21+ and present in OH. Gambling Problem? Call 1-800-GAMBLER.
Daily picks from betting experts on odds boosts and casino promos
