Cardinals vs 49ers NFL Week 3 – Match Preview & Live Updates Sunday, September 27, 2026

National Football League
49ers
Home
27/09/2026
4:05pm
Cardinals
Away

49ers vs. Cardinals: Detailed Breakdown

On Sunday, September 27, 2026, 49ers face Cardinals. The Point Spread is Cardinals , while the Total is 48.5 M/L: Cardinals -394, 49ers +312 is available. Sportsbetting sites have full lines listed.

Money Line -375 BetMGM +315 FanDuel
Spread -7.5 -105 BetMGM 7.5 -105 BetMGM
Over/Under -105 FanDuel FanDuel

Matchup Overview

  • Teams: 49ers vs Cardinals
  • Date: Sunday, September 27, 2026
  • Time: 04:05 pm ET
  • Venue: Levi's Stadium

Where To Watch 49ers vs Cardinals on Sunday

Watch the full match on FOX.

Injuries

49ers
Cardinals

Current Betting Odds

  • Spread: Cardinals favored at 7.5
  • Total (Over/Under): 48.5
  • Moneyline Odds: 49ers -394 , Cardinals +312

Recent Matches

49ers
Cardinals
Date Vs Result Score
09/20/2026 Dolphins win 35 : 13
09/10/2026 Rams win 7 : 27
08/27/2026 Raiders win 12 : 18
08/20/2026 Chargers win 17 : 41
08/13/2026 Titans loss 13 : 19
01/17/2026 Seahawks loss 41 : 6
01/11/2026 Eagles win 19 : 23
01/03/2026 Seahawks loss 3 : 13
12/28/2025 Bears win 42 : 38
12/22/2025 Colts win 27 : 48
W - 7
L - 3
Date Vs Result Score
09/20/2026 Seahawks loss 7 : 31
09/13/2026 Chargers win 14 : 26
08/28/2026 Packers loss 42 : 38
08/22/2026 Cowboys loss 13 : 34
08/15/2026 Raiders draw :
08/06/2026 Panthers loss 30 : 33
01/04/2026 Rams loss 37 : 20
12/28/2025 Bengals loss 37 : 14
12/21/2025 Falcons loss 19 : 26
12/14/2025 Texans loss 40 : 20
W - 1
D - 1
L - 8

Who Wins: our Prediction

Based on statistical analysis, we see the 49ers at a win probability of 23%, while the Cardinals have a propability of 77% to win.

Find the best Futures for 49ers vs Cardinals

Statistics

Want Even More Picks To Profit From?
Money Line -400 FanDuel +320 BetMGM
Spread -8.0 -108 BetMGM 7.5 -110 FanDuel
Over/Under -108 BetMGM FanDuel
Money Line +102 FanDuel -120 BetMGM
Spread 1.5 -110 BetMGM -1.5 -108 BetMGM
Over/Under -105 BetMGM BetMGM
Money Line -190 BetMGM +160 FanDuel
Spread -3.5 -108 BetMGM 3.5 -108 FanDuel
Over/Under -110 BetMGM BetMGM
Money Line +295 FanDuel -370 FanDuel
Spread 7.0 -105 FanDuel -7.0 -110 BetMGM
Over/Under -108 BetMGM BetMGM
Money Line +275 BetMGM -340 FanDuel
Spread 7.0 -110 BetMGM -7.0 -108 BetMGM
Over/Under -112 BetMGM BetMGM
Money Line +116 FanDuel -130 Fanatics
Spread 1.5 -102 FanDuel -2.0 -110 BetMGM
Over/Under -104 FanDuel BetMGM
Money Line -145 BetMGM +125 BetMGM
Spread -3.0 -102 BetMGM 2.5 +100 Fanatics
Over/Under -108 BetMGM BetMGM
Money Line -134 FanDuel +115 BetMGM
Spread -2.0 -110 BetMGM 1.5 -102 FanDuel
Over/Under -110 BetMGM BetMGM
Money Line -184 FanDuel +155 BetMGM
Spread -3.5 -108 BetMGM 3.5 -110 BetMGM
Over/Under -110 BetMGM BetMGM
Money Line +160 Fanatics -186 FanDuel
Spread 3.5 -110 BetMGM -3.5 -108 BetMGM
Over/Under -105 FanDuel BetMGM
Money Line -165 BetMGM +146 FanDuel
Spread -3.0 -112 BetMGM 3.0 -104 FanDuel
Over/Under -105 FanDuel BetMGM
Money Line +200 BetMGM -245 FanDuel
Spread 5.0 -108 BetMGM -5.5 -105 FanDuel
Over/Under -108 FanDuel FanDuel
Money Line -168 FanDuel +145 BetMGM
Spread -3.5 +100 Fanatics 3.0 -102 BetMGM
Over/Under -110 BetMGM BetMGM
Money Line -175 BetMGM +150 Fanatics
Spread -3.5 +100 Fanatics 3.5 -115 BetMGM
Over/Under -108 BetMGM Fanatics
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