Cardinals– is set for Sunday, October 12, 2025 at 1:00 pm ET. Sportsbooks list Point Spread Cardinals and Total 46.5 M/L: Cardinals -435, Colts +337 is available. Lines are posted across books.
Money Line-426+375
Spread
-8.5
-108
9.0
-110
Over/Under
+102
Matchup Overview
Teams: Colts vs Cardinals
Date: Sunday, October 12, 2025
Time: 01:00 pm ET
Venue: Lucas Oil Stadium
Where To Watch Colts vs Cardinals on Sunday
The match will be broadcast by FOX.
Injuries
Colts
Cardinals
Josh Downs
– Hamstring
D.J. Montgomery
– Undisclosed
Spencer Shrader
– Knee
Anthony Richardson Sr.
– Eye
Anthony Gould
– Illness
Charvarius Ward
– Concussion
Rigoberto Sanchez
– Personal
Adonai Mitchell
– Gameday Inactive
Michael Pittman Jr.
– Glute
Alec Pierce
– Knee
Riley Leonard
– Gameday Inactive
Ashton Dulin
– Concussion
Daniel Jones
– Fibula
Nick Cross
– Hip
DJ Giddens
– Gameday Inactive
Kenny Moore II
– Calf
Khalil Herbert
– Gameday Inactive
Justin Walley
– Knee
JuJu Brents
– Gameday Inactive
Hunter Wohler
– Foot
Tyler Goodson
– Elbow
Samuel Womack III
– Gameday Inactive
Johnathan Edwards
– Gameday Inactive
Salvon Ahmed
– Ankle
Daniel Scott
– Knee
Chris Lammons
– Foot
Jaylon Jones
– Hamstring
Zaire Franklin
– Ankle
Liam Anderson
– Undisclosed
Joe Bachie
– Quadricep
Maddux Trujillo
– Undisclosed
Kwity Paye
– Groin
Samson Ebukam
– Back
Jacob Phillips
– Bicep
Quenton Nelson
– Wrist
Jaylon Carlies
– Ankle
Austin Ajiake
– Throat
Cameron McGrone
– Achilles
Tanor Bortolini
– Concussion
Danny Pinter
– Rib
Luke Tenuta
– Gameday Inactive
Dalton Tucker
– Shoulder
Matt Goncalves
– Personal
Braden Smith
– Groin
Blake Freeland
– Leg
Jack Wilson
– Undisclosed
Bernhard Raimann
– Illness
Jelani Woods
– Gameday Inactive
Tyler Warren
– Toe
Drew Ogletree
– Neck
Will Mallory
– Gameday Inactive
Grover Stewart
– Biceps
JT Tuimoloau
– Gameday Inactive
Neville Gallimore
– Knee
Tyquan Lewis
– Oblique
Laiatu Latu
– Hamstring
Eric Johnson II
– Gameday Inactive
DeForest Buckner
– Back
Will Johnson
– Groin
Kyler Murray
– Illness
Mack Wilson Sr.
– Ankle
Budda Baker
– Hamstring
Greg Dortch
– Collarbone
Baron Browning
– Concussion
James Conner
– Ankle
BJ Ojulari
– Undisclosed
J.Sweat
– Ankle
Blake Gillikin
– Back
Kei'Trel Clark
– Gameday Inactive
Michael Wilson
– Foot
Quez Watkins
– Undisclosed
Max Melton
– Hamstring
Zay Jones
– Knee
Marvin Harrison Jr.
– Concussion
DeeJay Dallas
– Gameday Inactive
Garrett Williams
– Knee
Sean Murphy-Bunting
– Knee
Starling Thomas V
– Knee
Zaven Collins
– Hand
Jammie Robinson
– Gameday Inactive
Akeem Davis-Gaither
– Elbow
Elijah Jones
– Gameday Inactive
Denzel Burke
– Knee
Darren Hall
– Ankle
Emari Demercado
– Ankle
Joey Blount
– Neck
Trey Benson
– Knee
Jalen Thompson
– Hamstring
Bam Knight
– Gameday Inactive
Kitan Crawford
– Ankle
Jaylon Jones
– Hamstring
Dadrion Taylor-Demerson
– Ankle
Owen Pappoe
– Quadricep
Cody Simon
– Concussion
J.J. Russell
– Concussion
Xavier Thomas
– Gameday Inactive
Dante Stills
– Heel
Darius Robinson
– Chest
Hayden Conner
– Gameday Inactive
Jon Gaines II
– Thumb
Evan Brown
– Hamstring
Jeremiah Byers
– Gameday Inactive
Kelvin Beachum
– Knee
Valentin Senn
– Neck
Paris Johnson Jr.
– Knee
Hjalte Froholdt
– Elbow
Jonah Williams
– Foot
Christian Jones
– Knee
Josh Fryar
– Gameday Inactive
PJ Mustipher
– Gameday Inactive
Simi Fehoko
– Concussion
Travis Vokolek
– Gameday Inactive
Andre Baccellia
– Arm
Elijah Higgins
– Illness
Trishton Jackson
– Thumb
Tip Reiman
– Foot
Xavier Weaver
– Gameday Inactive
L.J. Collier
– Knee
Bilal Nichols
– Undisclosed
Dalvin Tomlinson
– Knee
Elijah Simmons
– Gameday Inactive
Walter Nolen III
– Calf
Justin Jones
– Knee
Current Betting Odds
Spread: Cardinals favored at 8
Total (Over/Under): 46.5
Moneyline Odds: Colts -435 , Cardinals +337
Recent Matches
Colts
Cardinals
Date
Vs
Result
Score
10/05/2025
Raiders
win
40
: 6
09/28/2025
Rams
loss
27 :
20
09/21/2025
Titans
win
20 :
41
09/14/2025
Broncos
win
29
: 28
09/07/2025
Dolphins
win
33
: 8
08/23/2025
Bengals
win
14 :
41
08/16/2025
Packers
loss
19
: 23
08/07/2025
Ravens
loss
24 :
16
01/05/2025
Jaguars
win
26
: 23
12/29/2024
Giants
loss
45 :
33
W - 6
L - 4
Date
Vs
Result
Score
10/05/2025
Titans
loss
21
: 22
09/25/2025
Seahawks
loss
20
: 23
09/21/2025
49ers
loss
16 :
15
09/14/2025
Panthers
win
27
: 22
09/07/2025
Saints
win
13 :
20
08/23/2025
Raiders
win
20
: 10
08/16/2025
Broncos
loss
27 :
7
08/09/2025
Chiefs
win
20
: 17
01/05/2025
49ers
win
47
: 24
12/28/2024
Rams
loss
13 :
9
W - 5
L - 5
Who Wins: our Prediction
Based on statistical analysis, we see the Colts at a win probability of 22%, while the Cardinals have a propability of 78% to win.
21+ and present in OH. Gambling Problem? Call 1-800-GAMBLER.
This site is using
Cloudflare
and adheres to the
Google Safe Browsing Program. We adapted
Google's Privacy Guidelines
to keep your data safe at all times.